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颌面重建中的个性化植入物:当前实践与未来方向——系统评价综述

Patient-Specific Implants in Maxillo-Facial Reconstruction: Current Practices and Way Forward-An Overview of Systematic Reviews.

作者信息

Kattimani Vivekanand, Sreeram Roopa Rani, Panga Gnana Sarita Kumari, Vasamsetti Divya Bhavani, Tiwari Rahul

机构信息

SIBAR Institute of Dental Sciences, Takkellapadu, Guntur, Andhra Pradesh 522509 India.

Vishnu Dental College, Bhimavaram, India.

出版信息

J Maxillofac Oral Surg. 2025 Aug;24(4):1075-1089. doi: 10.1007/s12663-025-02440-4. Epub 2025 Jan 15.

Abstract

BACKGROUND

Maxillofacial reconstruction has undergone a paradigm shift from conventional to digital workflows. The integration of Three Dimensional (3D) technology and patient-specific implants (PSIs) has revolutionized surgical planning and execution, particularly in complex procedures. This overview of systematic review (SR) aims to provide healthcare professionals with a comprehensive, evidence-based resource on current practices and future perspectives of maxillofacial reconstruction using 3D technology and PSIs.

METHODS

A comprehensive literature search was conducted from inception 30th September 2023, using keywords such as "3D printing," "patient-specific implants," "maxillofacial reconstruction," and related terms. The search included PubMed, ScienceDirect, and Cochrane databases. Only SRs focusing on maxillofacial reconstruction with 3D technology were included. Article quality was assessed using the AMSTAR (A MeaSurement Tool to Assess systematic Reviews) tool and Glenny et al. checklists.

RESULTS

Out of 327 search results, fourteen articles met the inclusion criteria. Most reviews focused on reconstructing orbital, nasal, maxillary, mandibular, and temporomandibular joint defects. Notably, only one Cochrane review was identified, indicating a lack of high-quality randomized or cohort studies. Furthermore, only three reviews had a registered protocol.

CONCLUSION

While the literature supports the use of PSIs and 3D technology in maxillofacial reconstruction, the evidence quality remains moderate to poor. The heterogeneity of the data across studies has limited the ability to perform a meta-analysis. SRs emphasize the need for careful ethical considerations when using medical devices like PSIs. Although advanced technologies enhance surgical outcomes, they come with a steep learning curve and require rigorous clinical validation.

摘要

背景

颌面重建已从传统工作流程向数字工作流程发生了范式转变。三维(3D)技术与定制植入物(PSI)的整合彻底改变了手术规划和实施方式,尤其是在复杂手术中。本系统评价(SR)综述旨在为医疗保健专业人员提供关于使用3D技术和PSI进行颌面重建的当前实践和未来前景的全面、循证资源。

方法

从2023年9月30日开始进行全面的文献检索,使用“3D打印”“定制植入物”“颌面重建”等关键词及相关术语。检索包括PubMed、ScienceDirect和Cochrane数据库。仅纳入专注于使用3D技术进行颌面重建的SR。使用AMSTAR(评估系统评价的测量工具)工具和Glenny等人的清单评估文章质量。

结果

在327条检索结果中,14篇文章符合纳入标准。大多数综述聚焦于眼眶、鼻、上颌骨、下颌骨和颞下颌关节缺损的重建。值得注意的是,仅识别出一篇Cochrane综述,表明缺乏高质量的随机或队列研究。此外,只有三篇综述有注册方案。

结论

虽然文献支持在颌面重建中使用PSI和3D技术,但证据质量仍然中等至较差。各研究数据的异质性限制了进行荟萃分析的能力。SR强调在使用PSI等医疗设备时需要仔细考虑伦理问题。尽管先进技术可改善手术效果,但它们存在陡峭的学习曲线,需要严格的临床验证。

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