Lees W R, Hall-Craggs M A, Manhire A
Clin Radiol. 1985 Sep;36(5):517-20. doi: 10.1016/s0009-9260(85)80204-x.
Four hundred and fifty-four unselected consecutive patients who underwent fine-needle aspiration biopsy between 1978 and 1983 were reviewed restrospectively. The overall sensitivity of the technique in the diagnosis of malignancy was 77%. When pancreatic and biliary masses were excluded, the sensitivity was 84%. The predictive value of a positive was 100% and of a negative, 65%. Reasons for false negative biopsies are analysed. Ways of increasing the sensitivity of the procedure and improving biopsy techniques are discussed. No significant complications were encountered. We conclude that the technique is valuable, safe and can be performed in any hospital with basic ultrasonographic and radiological equipment, provided that there is a cytology service.
对1978年至1983年间接受细针穿刺活检的454例未经挑选的连续患者进行了回顾性研究。该技术对恶性肿瘤诊断的总体敏感性为77%。排除胰腺和胆管肿块后，敏感性为84%。阳性预测值为100%，阴性预测值为65%。分析了假阴性活检的原因。讨论了提高该操作敏感性和改进活检技术的方法。未遇到严重并发症。我们得出结论，该技术是有价值的、安全的，并且只要有细胞学服务，在任何配备基本超声和放射设备的医院都可以进行。
