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一种罕见的、头孢菌素诱发的皮疹:急性泛发性脓疱性皮病。

A Rare, Cephalosporin-induced Rash: Acute Generalized Exanthematous Pustulosis.

作者信息

Colantonio Mark A, Sblendorio Danielle, Hart Elizabeth, Melemai Vincent, Wiley Joshua

机构信息

Department of Medicine, West Virginia University, PO Box 9168, Department of Medicine House Staff, 4 Floor HSC-N Morgantown, Morgantown, WV 26506, USA.

Department of Neurology, West Virginia University, PO Box 9180, WVU Neurology Department, 1 Medical Center Dr. Morgantown, Morgantown, WV 26506, USA.

出版信息

J Community Hosp Intern Med Perspect. 2025 Jul 3;15(4):104-107. doi: 10.55729/2000-9666.1512. eCollection 2025.

DOI:10.55729/2000-9666.1512
PMID:40757232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12315895/
Abstract

Acute generalized exanthematous pustulosis is an uncommon cause of rash, typically presenting with pustules with an erythematous base and associated skin-peeling. Frequently caused by medications, including penicillins and quinolones, cephalosporins are rarely reported as an offending agent. Here, we present a case of rare acute generalized exanthematous pustulosis secondary to recent cephalosporin use presenting to our rural healthcare facility. We aim to raise awareness of this unusual rash secondary to cephalosporin use.

摘要

急性泛发性脓疱性皮病是一种不常见的皮疹病因,典型表现为有红斑基底的脓疱并伴有皮肤脱屑。其常由药物引起,包括青霉素和喹诺酮类,头孢菌素很少被报道为致病因素。在此,我们报告一例继发于近期使用头孢菌素的罕见急性泛发性脓疱性皮病病例,该病例出现在我们的农村医疗机构。我们旨在提高对这种继发于头孢菌素使用的不寻常皮疹的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d2e/12315895/f0a15e0b52cc/jchim-15-04-104f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d2e/12315895/f0a15e0b52cc/jchim-15-04-104f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d2e/12315895/f0a15e0b52cc/jchim-15-04-104f1.jpg

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本文引用的文献

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J Eur Acad Dermatol Venereol. 2024 Nov;38(11):2073-2081. doi: 10.1111/jdv.20232. Epub 2024 Jul 18.
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Clinical features, diagnosis and management of cephalosporin-induced acute generalized exanthematous pustulosis.头孢菌素诱导的急性泛发性脓疱性皮疹的临床特征、诊断与管理
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Analysis of Types of Skin Lesions and Diseases in Everyday Infectious Disease Practice-How Experienced Are We?
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