Nabawanuka Brenda, Asiimwe Moses, Irumba Pauline, Aryampa Julian, Wasswa George, Muhoozi Michael, Amumpaire Peterson, Acen Joy, Katusabe Shamim, Tusabe Joan, Epuitai Joshua
Mountains of the Moon University, Fort Portal, Uganda.
Joint Clinical Research Center, Wakiso, Uganda.
PLoS One. 2025 Aug 4;20(8):e0311708. doi: 10.1371/journal.pone.0311708. eCollection 2025.
Puerperal sepsis remains one of the leading causes of maternal mortality and morbidity in Uganda.
This study assessed the prevalence and factors associated with puerperal sepsis among postpartum women at Fort portal Regional Referral Hospital located in western Uganda.
A cross-sectional design was employed in the study. We conducted a records review of the patient files of 180 postnatal mothers who were admitted at Fort Portal Regional Referral Hospital from 20 February, 2024 to 01 April, 2024. A data abstraction checklist was used to collect data from participant files based on strict inclusion and exclusion criteria. Data was entered in Microsoft Excel and exported to STATA17 for data analysis. Descriptive analysis and logistic regression analysis were performed to determine the prevalence of puerperal sepsis and determinants. Bivariate and multivariate logistic regression analysis was conducted for significant factors presented as Adjusted Odds Ratios (aOR) at p ≤ 0.05.
The median age of participants was 25.5 years (1QR = 20-30) and the majority (77%) had primary education. The prevalence of postnatal sepsis was 24%. Duration of hospital stay [aOR=2.30; 95%CI (1.552-3.398); p=<0.001], history of antepartum hemorrhage [aOR=29.09; 95% CI (1.182-716.38); p = 0.039] and Anemia [aOR=0.01; 95% CI (0.001-0.218); p = 0.004] were identified as factors associated with puerperal sepsis among postnatal women upon multivariate logistic regression.
Puerperal sepsis was common in our setting. This study found that mode of delivery, duration of hospital stay, anemia, and Antepartum hemorrhage, were the determining factors contributing to puerperal sepsis, infection prevention measures during cesarean sections, and reducing the length of hospital stay would prove to be beneficial in the prevention of sepsis.
产后败血症仍然是乌干达孕产妇死亡和发病的主要原因之一。
本研究评估了乌干达西部福特portal地区转诊医院产后妇女产后败血症的患病率及其相关因素。
本研究采用横断面设计。我们对2024年2月20日至2024年4月1日在福特portal地区转诊医院住院的180名产后母亲的病历进行了回顾。根据严格的纳入和排除标准，使用数据提取清单从参与者的病历中收集数据。数据录入Microsoft Excel并导出到STATA17进行数据分析。进行描述性分析和逻辑回归分析以确定产后败血症的患病率和决定因素。对呈现为调整优势比（aOR）且p≤0.05的显著因素进行二元和多变量逻辑回归分析。
参与者的中位年龄为25.5岁（1QR=20-30），大多数（77%）接受过小学教育。产后败血症的患病率为24%。住院时间[aOR=2.30；95%CI（1.552-3.398）；p<0.001]、产前出血史[aOR=29.09；95%CI（1.182-716.38）；p=0.039]和贫血[aOR=0.01；95%CI（0.001-0.218）；p=0.004]在多变量逻辑回归中被确定为产后妇女产后败血症的相关因素。
产后败血症在我们的研究环境中很常见。本研究发现，分娩方式、住院时间、贫血和产前出血是导致产后败血症的决定因素，剖宫产期间的感染预防措施以及缩短住院时间将有助于预防败血症。
