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三端口双手操作技术在玻璃体切除术中直接全氟碳液体 - 硅油置换治疗晚期增生性玻璃体视网膜病变的疗效

The efficacy of the three-port bimanual technique for direct perfluorocarbon liquid-silicone oil exchange in vitrectomy for the treatment of advanced proliferative vitreoretinopathy.

作者信息

Zhang Zhou, Zhang Xi, Wang Mei, Chen Peng, Ding Guoxin, Wang Xian, Li Yingqi

机构信息

The Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, Guizhou, China.

Aier Eye Hospital (Gui Yang), Changsha, China.

出版信息

BMC Ophthalmol. 2025 Aug 4;25(1):445. doi: 10.1186/s12886-025-04281-8.

Abstract

PURPOSE

To evaluate the therapeutic effect of three-port, bimanual technique for direct perfluorocarbon liquid (PFCL)-silicone oil (SO) exchange in avoiding retinal re-detachment and shortening the surgical duration in 23-gauge (23 G) pars plana vitrectomy (PPV) for the treatment of advanced proliferative vitreoretinopathy (PVR) complicating primary rhegmatogenous retinal detachment (RRD).

METHODS

A Retrospective, comparative, consecutive, single-center study was conducted. Fifty-one eyes of 51 patients diagnosed with RRD complicated by PVR at the severe C stage, according to the standardized grading system, were retrospectively reviewed over a 3-year period. All patients underwent three-port 23 G PPV following a standardized protocol. Twenty-three eyes underwent the bimanual technique for direct PFCL-SO exchange during the final surgical steps, while twenty-eight eyes received conventional air-fluid exchange (AFE) for PFCL removal before SO tamponade. Primary outcome measures included visual acuity (logMAR), retinal status, intraocular pressure (IOP), surgical time and incidence of intraoperative and postoperative complications over a minimum 12-month follow-up period.

RESULTS

The primary anatomical success rate was 86.9% in the bimanual group versus 85.7% in the AFE group (P = 0.898). Visual acuity on postoperative day 1 was significantly improved in the bimanual group compared with the AFE group (P = 0.022). The surgical duration of bimanual group was significantly reduced compared to that of AFE group (P < 0.001). Two eyes in AFE group developed intraocular lens decentration during the surgical procedure. No statistically significant differences were observed in the incidence of postoperative complications between groups.

CONCLUSION

The bimanual technique for direct PFCL-SO exchange is advantageous for enhancing the efficiency of surgical procedures, reducing the incidence of intraoperative complications and maintaining the re-flattened retina in the process of PFCL aspiration and SO injection. This novel approach presents a feasible and cost-effective strategy to enhance both operational efficiency and rapid visual rehabilitation in the immediate postoperative period.

摘要

目的

评估三通道双手操作技术在23G玻璃体切割术(PPV)中进行全氟碳液体(PFCL)-硅油(SO)直接置换,以避免视网膜再次脱离并缩短手术时间,用于治疗合并原发性孔源性视网膜脱离(RRD)的晚期增生性玻璃体视网膜病变(PVR)的疗效。

方法

进行一项回顾性、比较性、连续性、单中心研究。根据标准化分级系统,对51例诊断为严重C期RRD合并PVR患者的51只眼进行了为期3年的回顾性分析。所有患者均按照标准化方案接受三通道23G PPV手术。23只眼在最后手术步骤中采用双手操作技术进行PFCL-SO直接置换,而28只眼在SO填塞前接受传统的气液交换(AFE)以去除PFCL。主要观察指标包括在至少12个月的随访期内的视力(logMAR)、视网膜状态、眼压(IOP)、手术时间以及术中及术后并发症的发生率。

结果

双手操作组的主要解剖成功率为86.9%,AFE组为85.7%(P = 0.898)。与AFE组相比,双手操作组术后第1天的视力有显著改善(P = 0.022)。双手操作组的手术时间明显短于AFE组(P < 0.001)。AFE组有2只眼在手术过程中出现人工晶状体偏位。两组术后并发症的发生率无统计学显著差异。

结论

PFCL-SO直接置换的双手操作技术有利于提高手术效率,降低术中并发症的发生率,并在PFCL抽吸和SO注入过程中维持视网膜的重新复位。这种新方法为提高手术效率和术后早期快速视力恢复提供了一种可行且具有成本效益的策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba71/12323066/db1f5c1bedaf/12886_2025_4281_Fig1_HTML.jpg

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