高血压性心脏病：它真的是一种病理学上的疾病吗？
Hypertensive heart disease: is it really a pathology?
作者信息
Bellicini Maria Giulia
机构信息
Institute of Cardiology, Spedali Civili di Brescia, Brescia, Italy.
出版信息
Hypertens Res. 2025 Aug 4. doi: 10.1038/s41440-025-02312-x.
PMID:40760163
Abstract
Hypertensive heart disease is not a direct cause of heart failure. Left ventricular hypertrophy is common in hypertension but rarely progresses to HFpEF or HFrEF. The true cardiovascular consequences of hypertension are primarily mediated by atherosclerosis and microvascular dysfunction, leading to stroke and myocardial infarction.
摘要
高血压性心脏病并非心力衰竭的直接病因。左心室肥厚在高血压患者中很常见，但很少进展为射血分数保留的心力衰竭（HFpEF）或射血分数降低的心力衰竭（HFrEF）。高血压真正的心血管后果主要由动脉粥样硬化和微血管功能障碍介导，进而导致中风和心肌梗死。
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