Leaper D J, Foster M E, Brennan S S, Davies P W
Equine Vet J. 1985 May;17(3):178-80. doi: 10.1111/j.2042-3306.1985.tb02463.x.
Magnetic fields have been considered for treating many ailments over man's history. There have been many anecdotal unsupported claims for successful treatment of soft tissue injury although reports have been more substantive in the orthopaedic field. The widespread clinical and veterinary use of a light self-adhesive magnetic foil in Europe prompted this trial of experimental wound healing. One hundred and sixty Sprague-Dawley rats had a linear 2.5 cm incision or a circular 1 cm skin defect made over the mid-dorsal spine. Equal numbers were randomised to receive either a magnetic foil or a dummy (control) dressing. At three, seven, 10 or 14 days linear wounds were distracted using a tensiometer; open defects were measured, excised and assayed for collagen content; 14-day wounds were examined histologically. Although wound tensile strengths increased and open wounds decreased in size with increase of hydroxyproline, there were no statistically significant differences between treated or control animals. Although easy to apply the alternate magnetic foil (giving 400 Gauss at 7 mm) conferred no statistically significant effect on soft tissue healing.
在人类历史上，磁场已被用于治疗多种疾病。尽管在骨科领域的报道更具实质性内容，但对于软组织损伤的成功治疗，已有许多未经证实的轶事性说法。欧洲一种轻便自粘磁性箔片在临床和兽医领域的广泛应用促使了此次实验性伤口愈合试验。160只斯普拉格-道利大鼠在脊柱中背部制作了一条2.5厘米的线性切口或一个1厘米的圆形皮肤缺损。将数量相等的大鼠随机分为两组，分别接受磁性箔片或假敷料（对照）。在第3、7、10或14天，使用张力计测量线性伤口的拉力；测量开放性缺损的大小，切除并检测其胶原蛋白含量；对14天的伤口进行组织学检查。尽管随着羟脯氨酸含量的增加，伤口抗张强度增加，开放性伤口尺寸减小，但治疗组和对照组动物之间没有统计学上的显著差异。尽管易于应用的交变磁性箔片（在7毫米处产生400高斯的磁场）对软组织愈合没有统计学上的显著影响。
