Samari Saif, Oliveira Ana, Brister Danica, Kum Elena, Aaron Shawn D, Adamko Darryl, Bhalla Anurag, Carlsten Christopher, Cormier Maxime, Ellis Anne K, Field Stephen K, Godbout Krystelle, Hernandez Paul, Hirota Jeremy A, Kaplan Alan, Kovesi Tom, Mancopes Renata, Sedeno Maria, Smith Maeve, Newman Robert, King Philip, Gallagher Tiffany, Butson Sarah, Brooks Dina, Satia Imran
Department of Medicine, McMaster University, Hamilton, ON, Canada.
Joint first co-authors.
ERJ Open Res. 2025 Aug 4;11(4). doi: 10.1183/23120541.01370-2024. eCollection 2025 Jul.
Chronic cough significantly impacts individuals' quality of life and poses challenges for healthcare providers due to limited licensed treatments, side effects of available medications and difficulty accessing nonpharmacological interventions. Understanding priorities for research, education and knowledge dissemination from the perspectives of individuals with chronic cough and healthcare providers can guide future efforts. This study aimed to identify these key priorities in Canada.
We conducted a cross-sectional study using the James Lind Alliance (JLA) method to set priorities. Chronic cough was identified as the healthcare problem. Participants rated items related to research, education and knowledge dissemination in an online survey using a seven-point Likert scale. Results of the survey were reviewed by the Canadian Thoracic Society's (CTS) multidisciplinary working group and patient partners who engaged in a face-to-face Priority-Setting Partnership, to establish a "Top 10" priorities list for chronic cough.
74 individuals with chronic cough and 62 healthcare providers completed the scoping survey. The top-rated priorities included enhancing knowledge of existing treatments, developing new treatments and improving diagnostic testing. The final "Top 10" priorities list emphasised the need for developing infrastructure for evaluating new treatments, improving understanding of biological mechanisms and raising awareness among the public and policymakers.
This is the first priority-setting project for chronic cough, highlighting key areas to address in research, education and dissemination. The identified priorities will serve as a foundation for future efforts to improve the management and care of individuals with chronic cough.
慢性咳嗽严重影响个人生活质量，且由于获批治疗方法有限、现有药物存在副作用以及难以获得非药物干预措施，给医疗服务提供者带来了挑战。从慢性咳嗽患者和医疗服务提供者的角度了解研究、教育和知识传播的优先事项，可为未来的工作提供指导。本研究旨在确定加拿大的这些关键优先事项。
我们采用詹姆斯·林德联盟（JLA）方法进行了一项横断面研究以确定优先事项。慢性咳嗽被确定为医疗问题。参与者在一项在线调查中使用七点李克特量表对与研究、教育和知识传播相关的项目进行评分。加拿大胸科学会（CTS）的多学科工作组和患者合作伙伴对调查结果进行了审查，他们参与了面对面的优先事项确定合作，以建立慢性咳嗽的“十大”优先事项清单。
74名慢性咳嗽患者和62名医疗服务提供者完成了范围界定调查。排名最高的优先事项包括增强对现有治疗方法的了解、开发新的治疗方法以及改进诊断测试。最终的“十大”优先事项清单强调了建立评估新治疗方法的基础设施、增进对生物学机制的理解以及提高公众和政策制定者意识的必要性。
这是首个针对慢性咳嗽的优先事项确定项目，突出了研究、教育和传播中需要解决的关键领域。确定的优先事项将为未来改善慢性咳嗽患者的管理和护理工作奠定基础。
