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Cytochrome P450 genotype polymorphisms and suboptimal voriconazole serum level in a patient with invasive cerebral fungal infection.

作者信息

Champagne William, Malek Alexandre E

机构信息

Division of Infectious Diseases, Department of Medicine, School of Medicine, LSU Health Shreveport, LA 71103, United States.

出版信息

IDCases. 2025 Jul 27;41:e02332. doi: 10.1016/j.idcr.2025.e02332. eCollection 2025.

Abstract
摘要

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本文引用的文献

1
Clinical drug interactions between voriconazole and 38 other drugs: a retrospective analysis of adverse events.
Front Pharmacol. 2024 Sep 30;15:1292163. doi: 10.3389/fphar.2024.1292163. eCollection 2024.
2
Multidisciplinary Insights into the Structure-Function Relationship of the CYP2B6 Active Site.
Drug Metab Dispos. 2023 Mar;51(3):369-384. doi: 10.1124/dmd.122.000853. Epub 2022 Nov 23.
3
Plausible drug interaction between cyclophosphamide and voriconazole via inhibition of CYP2B6.
Drug Metab Pharmacokinet. 2021 Aug;39:100396. doi: 10.1016/j.dmpk.2021.100396. Epub 2021 Apr 12.
4
Effect of Therapeutic Drug Monitoring and Cytochrome P450 2C19 Genotyping on Clinical Outcomes of Voriconazole: A Systematic Review.
Ann Pharmacother. 2021 Apr;55(4):509-529. doi: 10.1177/1060028020948174. Epub 2020 Aug 8.
6
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP2C19 and Voriconazole Therapy.
Clin Pharmacol Ther. 2017 Jul;102(1):45-51. doi: 10.1002/cpt.583. Epub 2017 Apr 18.
7
Inhibition of Cytochrome P450 2B6 Activity by Voriconazole Profiled Using Efavirenz Disposition in Healthy Volunteers.
Antimicrob Agents Chemother. 2016 Oct 21;60(11):6813-6822. doi: 10.1128/AAC.01000-16. Print 2016 Nov.
8
Voriconazole pharmacokinetics and exposure-response relationships: assessing the links between exposure, efficacy and toxicity.
Int J Antimicrob Agents. 2014 Sep;44(3):183-93. doi: 10.1016/j.ijantimicag.2014.05.019. Epub 2014 Jul 7.

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