Khound Murchana, Kaushik Jaya Shankar, Nath Abhishek, Das Bipul Kumar, Das Dhrubajyoti, Goswami Gourav, Sharma Diksha
Department of Pediatrics, All India Institute of Medical Sciences (AIIMS), Guwahati, Assam, India.
Cross-Disability Early Intervention Center (CDEIC), All India Institute of Medical Sciences (AIIMS), Guwahati, Assam, India.
Indian Pediatr. 2025 Sep;62(9):686-691. doi: 10.1007/s13312-025-00156-9. Epub 2025 Aug 5.
To develop and validate the Assamese version of the Rashtriya Bal Swasthya Karyakram (RBSK) screening tool for developmental delay (1-72 months) and autism (15-24 months) and to assess its diagnostic accuracy in comparison with the Developmental Profile-3 (DP-3) and the All India Institute of Medical Sciences (AIIMS)-Modified INCLEN Diagnostic Tool for autism spectrum disorder (INDT-ASD).
A cross-sectional study was conducted from January to December 2024 at a tertiary care hospital in India. The RBSK screening tool for developmental delay and autism was translated into Assamese through a standardized process involving forward translation, back-translation, expert review, and pilot testing (n = 10). Children aged 1-72 months were recruited from the outpatient department. Developmental delay was assessed using the Developmental Profile-3 (DP-3) and ASD in children aged 15-24 months using the AIIMS-Modified INCLEN Diagnostic Tool for Autism Spectrum Disorder (INDT-ASD) tool. Diagnostic accuracy was assessed by calculating sensitivity, specificity, positive and negative predictive values, Cohen's kappa statistic, and area under receiver operating characteristic (AUROC) curves.
A total of 139 children with mean (SD) age 30.5 (12.2 months) were enrolled. The Assamese version of the RBSK screening tool demonstrated a sensitivity and specificity of 94.1% and 84.9%, respectively, for developmental delay, and 89.5% and 93.8%, respectively, for ASD. Agreement with reference tools was high (Cohen's kappa = 0.85 for DP-3, 0.83 for AIIMS-Modified INDT-ASD). The tool showed excellent discriminative performance with AUROC (95%CI) of 0.94 (0.89, 0.98) for developmental delay and 0.92 (0.85, 0.98) for ASD.
The validated Assamese version of the RBSK screening tool for developmental delay and autism is an accurate screening tool in Assamese-speaking population.
开发并验证阿萨姆语版的国家儿童健康计划（RBSK）发育迟缓（1 - 72个月）和自闭症（15 - 24个月）筛查工具，并与发育概况-3（DP - 3）以及全印度医学科学研究所（AIIMS）修改后的自闭症谱系障碍印度国家儿童健康计划诊断工具（INDT - ASD）相比，评估其诊断准确性。
2024年1月至12月在印度一家三级护理医院进行了一项横断面研究。发育迟缓和自闭症的RBSK筛查工具通过包括正向翻译、回译、专家评审和预试验（n = 10）的标准化流程翻译成阿萨姆语。从门诊部招募了1 - 72个月的儿童。使用发育概况-3（DP - 3）评估发育迟缓，使用AIIMS修改后的自闭症谱系障碍印度国家儿童健康计划诊断工具（INDT - ASD）评估15 - 24个月儿童的自闭症谱系障碍（ASD）。通过计算敏感性、特异性以及阳性和阴性预测值、科恩kappa统计量和受试者工作特征曲线下面积（AUROC）来评估诊断准确性。
共纳入139名平均（标准差）年龄为30.5（12.2个月）的儿童。阿萨姆语版的RBSK筛查工具对发育迟缓的敏感性和特异性分别为94.1%和84.9%，对自闭症谱系障碍（ASD）的敏感性和特异性分别为89.5%和93.8%。与参考工具的一致性较高（DP - 3的科恩kappa = 0.85，AIIMS修改后的INDT - ASD的科恩kappa = 0.83）。该工具显示出优异的判别性能，发育迟缓的AUROC（95%CI）为0.94（从0.89到0.98），自闭症谱系障碍（ASD）的AUROC（95%CI）为0.92（从0.85到0.98）。
经过验证的阿萨姆语版RBSK发育迟缓和自闭症筛查工具是一种针对说阿萨姆语人群的准确筛查工具。
