Liu Xian-Yan, Shan Fa-Cheng, Li Hui, Zhu Jian-Bo
Department of Respiratory Medicine, Binzhou People's Hospital, Binzhou, Shandong, China.
Department of Radiotherapy, Binzhou People's Hospital, Binzhou, Shandong, China.
Clinics (Sao Paulo). 2025 Aug 4;80:100734. doi: 10.1016/j.clinsp.2025.100734.
To evaluate the effectiveness of AI-based chest Computed Tomography (CT) in a Multidisciplinary Diagnosis and Treatment (MDT) model for differentiating benign and malignant pulmonary nodules.
This retrospective study screened a total of 87 patients with pulmonary nodules who were treated between January 2019 and December 2020 at Binzhou People's Hospital, Qingdao Municipal Hospital, and Laiwu People's Hospital. AI analysis, MDT consultation, and a combined diagnostic approach were assessed using postoperative pathology as the reference standard.
Among 87 nodules, 69 (79.31 %) were malignant, and 18 (20.69 %) were benign. AI analysis showed moderate agreement with pathology (κ = 0.637, p < 0.05), while MDT and the combined approach demonstrated higher consistency (κ = 0.847, 0.888, p < 0.05). Sensitivity and specificity were as follows: AI (89.86 %, 77.78 %, AUC = 0.838), MDT (100 %, 77.78 %, AUC = 0.889), and the combined approach (100 %, 83.33 %, AUC = 0.917). The accuracy of the combined method (96.55 %) was superior to MDT (95.40 %) and AI alone (87.36 %) (p < 0.05).
AI-based chest CT combined with MDT may improve diagnostic accuracy and shows potential for broader clinical application.
评估基于人工智能的胸部计算机断层扫描(CT)在多学科诊断与治疗(MDT)模式下鉴别肺结节良恶性的有效性。
这项回顾性研究筛选了2019年1月至2020年12月期间在滨州市人民医院、青岛市市立医院和莱芜市人民医院接受治疗的87例肺结节患者。以术后病理为参考标准,评估人工智能分析、MDT会诊及联合诊断方法。
87个结节中,69个(79.31%)为恶性,18个(20.69%)为良性。人工智能分析与病理结果显示中度一致性(κ = 0.637,p < 0.05),而MDT及联合诊断方法显示出更高的一致性(κ = 0.847,0.888,p < 0.05)。敏感性和特异性如下:人工智能分析(89.86%,77.78%,AUC = 0.838),MDT(100%,77.78%,AUC = 0.889),联合诊断方法(100%,83.33%,AUC = 0.917)。联合诊断方法的准确性(96.55%)优于MDT(95.40%)和单独使用人工智能分析(87.36%)(p < 0.05)。
基于人工智能的胸部CT联合MDT可提高诊断准确性,并显示出更广泛临床应用的潜力。