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安全网人群中基于远程团队的高血压管理的心血管健康标志物

Cardiovascular Health Markers with Remote Team-Based Hypertension Management in a Safety-Net Population.

作者信息

Chervonski Ethan, Pelegri Elan, Calle Franzenith De La, Mandal Soumik, Graves Claire A, Colella Doreen, Elmaleh-Sachs Arielle, Nay Jacalyn, Dapkins Isaac, Schoenthaler Antoinette

机构信息

New York University Grossman School of Medicine, New York, NY.

Family Health Centers, New York University Langone Health, New York, NY.

出版信息

Am J Prev Med. 2025 Aug 3:108031. doi: 10.1016/j.amepre.2025.108031.

Abstract

INTRODUCTION

The impact of remote patient monitoring (RPM) for hypertension (HTN) on cardiovascular health (CVH) remains ill-defined. This study characterized the association between a RPM, team-based HTN intervention and CVH markers.

METHODS

This retrospective, single-arm cohort study included patients with uncontrolled HTN enrolled February 2022-July 2024 in the ALTA trial (clinicaltrials.gov NCT03713515) at five safety-net practices. The ALTA intervention involves RPM supported by a virtual clinic including a nurse practitioner (NP), registered nurse, and community health worker. Demographics, ALTA utilization, and CVH markers (blood pressure [BP], lipids, glycemic indicators, body mass index [BMI], and smoking) at baseline and 12 months were collected. Five markers were scored (0=poor, 1=intermediate, 2=ideal) and summed into a CVH score. The primary endpoint was the 12-month CVH score change in patients with baseline score ≤7. Secondary endpoints included individual non-BP marker changes in patients with baseline derangements.

RESULTS

Among 568 patients (mean age: 56 years), most were female, non-Hispanic Black, and English-speaking. NP visits were more common among females (p=0.04); no other demographics predicted ALTA utilization. The CVH score improved from 4.5 to 5.2 (n=196, p<0.001), independent of ALTA utilization. Total cholesterol (n=86, p<0.001), LDL (n=128, p<0.001), and triglycerides (n=51, p=0.004) improved. Hemoglobin A1c (n=195) dropped among patients with ≥1 NP visit (p=0.02). Fasting glucose (n=135) and BMI (n=289) decreased in the highest tertile of NP visits (p=0.03) and RPM (p=0.02), respectively. 4 of 27 patients quit smoking.

CONCLUSIONS

RPM with team-based support was associated with CVH improvements. Benefits may depend on intervention utilization.

摘要

引言

远程患者监测(RPM)对高血压(HTN)患者心血管健康(CVH)的影响仍不明确。本研究旨在明确RPM、基于团队的高血压干预措施与CVH标志物之间的关联。

方法

这项回顾性单臂队列研究纳入了2022年2月至2024年7月在五项安全网实践中参加ALTA试验(clinicaltrials.gov NCT03713515)的血压控制不佳的高血压患者。ALTA干预措施包括由虚拟诊所提供支持的RPM,该虚拟诊所配备一名执业护士(NP)、一名注册护士和一名社区卫生工作者。收集了患者的人口统计学信息、ALTA干预措施的使用情况以及基线和12个月时的CVH标志物(血压[BP]、血脂、血糖指标、体重指数[BMI]和吸烟情况)。对五项标志物进行评分(0=差,1=中等,2=理想),并汇总成一个CVH评分。主要终点是基线评分≤7的患者12个月时CVH评分的变化。次要终点包括基线指标异常的患者个体非血压标志物的变化。

结果

在568名患者(平均年龄:56岁)中,大多数为女性、非西班牙裔黑人且说英语。NP问诊在女性中更为常见(p=0.04);没有其他人口统计学特征能够预测ALTA干预措施的使用情况。CVH评分从4.5提高到了5.2(n=196,p<0.001),与ALTA干预措施的使用情况无关。总胆固醇(n=86,p<0.001)、低密度脂蛋白(n=128,p<0.001)和甘油三酯(n=51,p=0.004)有所改善。在接受≥1次NP问诊的患者中,糖化血红蛋白(n=195)有所下降(p=0.0

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