Vega-Retuerta Nerea, Sánchez-Parente Sandra, Segura-Jiménez Víctor
Faculty of Physical Activity and Sport Sciences-INEF, Universidad Politécnica de Madrid, Madrid, Spain.
GALENO research group, Department of Physical Education, Faculty of Education Sciences, University of Cádiz, Cádiz, Spain; Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), Cádiz, Spain.
Prev Med. 2025 Oct;199:108381. doi: 10.1016/j.ypmed.2025.108381. Epub 2025 Aug 5.
To determine the effectiveness of multidisciplinary interventions including exercise in improving health outcomes for patients with non-specific chronic low back pain (NSCLBP) across different regions.
The search for studies was not restricted to a specific time period but was conducted based on the availability of existing literature within the selected databases. A comprehensive literature search was conducted in four databases: EBSCOhost (from 1995), PubMed (from 1996), Web of Science (from 1964), and Scopus (from 2004), up to November 3, 2021. After applying exclusion criteria, 31 studies published between 1998 and 2021 were selected for final inclusion. The methodological approach included both qualitative and quantitative analyses, ensuring a comprehensive evaluation of the available evidence.
Multidisciplinary interventions including exercise aimed at relieving symptoms of NSCLBP were included. Outcomes analyzed were disability, pain, fear avoidance, quality of life, perceived change, depression, anxiety and stress. The Comprehensive Meta-Analysis software was used for statistical analyses.
Thirty-one studies were included in the qualitative analysis and 29 in the meta-analysis. The qualitative analysis showed improvements in favor of the intervention group (IG) in pain, fear avoidance, quality of life and perceived change. The meta-analysis reported significant pooled effect size (ES) in favor of the IGs in disability, pain, fear avoidance, quality of life, and perceived change among patients with NSCLBP.
Multidisciplinary approaches including exercise appear to be effective in reducing disability, pain, fear avoidance, quality of life and perceived change, but not depression, anxiety or stress in patients with NSCLBP. The findings should be interpreted cautiously in light of substantial heterogeneity and the limited quality of the available evidence.
确定包括运动在内的多学科干预措施对不同地区非特异性慢性下腰痛（NSCLBP）患者改善健康结局的有效性。
对研究的检索不限于特定时间段，而是根据所选数据库中现有文献的可获取性进行。在四个数据库中进行了全面的文献检索：EBSCOhost（始于1995年）、PubMed（始于1996年）、科学网（始于1964年）和Scopus（始于2004年），截至2021年11月3日。应用排除标准后，最终纳入了1998年至2021年发表的31项研究。方法学方法包括定性和定量分析，以确保对现有证据进行全面评估。
纳入旨在缓解NSCLBP症状的包括运动在内的多学科干预措施。分析的结局包括残疾、疼痛、恐惧回避、生活质量、感知变化、抑郁、焦虑和压力。使用综合荟萃分析软件进行统计分析。
定性分析纳入了31项研究，荟萃分析纳入了29项研究。定性分析显示，干预组（IG）在疼痛、恐惧回避、生活质量和感知变化方面有所改善。荟萃分析报告，在NSCLBP患者中，IG组在残疾、疼痛、恐惧回避、生活质量和感知变化方面有显著的合并效应量（ES）。
包括运动在内的多学科方法似乎对降低NSCLBP患者的残疾、疼痛、恐惧回避、生活质量和感知变化有效，但对抑郁、焦虑或压力无效。鉴于存在大量异质性和现有证据质量有限，对这些发现应谨慎解读。
