Kusters Mike P T, Bouhuys Marleen, Vernooij Robin W M, Huis In 't Veld Linde F, van Limbergen Johan E, Yang Bada, van Rheenen Patrick F
Cochrane Netherlands, Julius Center for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands.
Department of Pediatric Gastroenterology, Hepatology and Nutrition, University of Groningen, University Medical Centre Groningen, Beatrix Children's Hospital, PO Box 30001, 9700 RB, Groningen, the Netherlands.
Eur J Pediatr. 2025 Aug 5;184(8):531. doi: 10.1007/s00431-025-06341-z.
Telemonitoring could be an alternative for standard face-to-face consultations. In adults with inflammatory bowel disease (IBD), telemonitoring has been associated with improved quality of life (QoL) and reduced costs. We aimed to assess whether telemonitoring of adolescents with IBD is non-inferior to standard care in controlling disease activity. We searched Medline and Embase up to June 15, 2025, for randomized trials comparing the effect of telemonitoring and standard care on disease activity in adolescents with IBD. Secondary outcomes were QoL, costs, patient satisfaction, patient adherence, face-to-face contacts, and emergency room attendances or hospitalizations. Risk of bias and certainty of evidence were assessed using the Risk of Bias 2 tool and GRADE, respectively. Data was synthesized and reported in accordance with the Synthesis Without Meta-analysis (SWiM) reporting guideline and the Cochrane Handbook. Three studies (309 patients) were identified. Risk of bias was judged "high" for one study and as "some concerns" for the remaining two studies. We found that telemonitoring may not worsen disease activity (low-certainty evidence) and may result in little to no improvement in QoL (low-certainty evidence) compared to standard care. Telemonitoring likely results in a slight cost reduction (moderate- certainty evidence).
Telemonitoring may be non-inferior to standard care in controlling disease activity for adolescents with IBD.
• Studies comparing telemonitoring with standard follow-up in adults with inflammatory bowel disease (IBD) did not find a difference in disease activity or the occurrence of flares between these strategies. • Telemonitoring could improve quality of life and reduce costs and health care utilization in adults.
• This systematic review exclusively reviews the effect of telemonitoring on adolescents with IBD. • Based on limited evidence, following adolescents with IBD with telemonitoring appears to be safe and may reduce the number of outpatient visits and societal costs.
远程监测可能是标准面对面咨询的一种替代方式。在患有炎症性肠病（IBD）的成年人中，远程监测与生活质量（QoL）改善和成本降低相关。我们旨在评估IBD青少年的远程监测在控制疾病活动方面是否不劣于标准护理。我们检索了截至2025年6月15日的Medline和Embase，以查找比较远程监测和标准护理对IBD青少年疾病活动影响的随机试验。次要结局包括生活质量、成本、患者满意度、患者依从性、面对面接触以及急诊就诊或住院情况。分别使用偏倚风险2工具和GRADE评估偏倚风险和证据确定性。数据根据非Meta分析的综合（SWiM）报告指南和Cochrane手册进行综合和报告。确定了三项研究（309名患者）。一项研究的偏倚风险被判定为“高”，其余两项研究的偏倚风险为“有些担忧”。我们发现，与标准护理相比，远程监测可能不会使疾病活动恶化（低确定性证据），并且可能导致生活质量几乎没有改善（低确定性证据）。远程监测可能会导致成本略有降低（中等确定性证据）。
对于IBD青少年，远程监测在控制疾病活动方面可能不劣于标准护理。
• 比较炎症性肠病（IBD）成人患者远程监测与标准随访的研究未发现这些策略在疾病活动或发作发生率方面存在差异。
• 远程监测可改善成人的生活质量并降低成本和医疗保健利用率。
• 本系统评价专门回顾了远程监测对IBD青少年的影响。
• 基于有限的证据，对IBD青少年进行远程监测似乎是安全的，并且可能减少门诊就诊次数和社会成本。
