同一枚硬币的两面：初级保健试验中的招募表现与感知工作量——来自AgeWell.de研究的见解

Two sides of the same coin: recruitment performance and perceived workload in primary care trials-insights from the AgeWell.de study.

作者信息

Sanftenberg Linda, Kosilek Robert Philipp, Birnberger Lorenz, Schillok Hannah, Wittmann Felix, Luppa Melanie, Blawert Anne, Boekholt Melanie, Brettschneider Christian, König Hans-Helmut, Bauer Alexander, Weise Solveig, Frese Thomas, Kaduszkiewicz Hanna, Döhring Juliane, Escales Catharina, Thyrian Jochen René, Wiese Birgitt, Riedel-Heller Steffi G, Gensichen Jochen

机构信息

Institute of General Practice and Family Medicine, University Hospital, LMU Munich, 80336, Munich, Germany.

Medical Faculty, Leipzig, Institute of Social Medicine, Occupational Health and Public Health (ISAP), 04103, Leipzig, Germany.

出版信息

BMC Prim Care. 2025 Aug 5;26(1):243. doi: 10.1186/s12875-025-02948-1.

DOI:10.1186/s12875-025-02948-1

PMID:40764906

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12326823/

Abstract

BACKGROUND

Recruitment through general practitioners (GPs) is a key challenge in primary care trials. Understanding how individual, practice, and regional characteristics affect recruitment and perceived workload could help optimize participation strategies. This study aims to identify barriers and facilitators to patient recruitment within the AgeWell.de dementia prevention trial.

METHODS

We analysed publicly available data on GPs participating in the AgeWell.de trial, including their sociodemographic characteristics, practice structures, and socioeconomic indicators of their practice locations, alongside recruitment and survey data. We used correlation analysis and uni- and multivariable regression models to explore determinants of study engagement in terms of recruitment performance and perceived workload.

RESULTS

Among 120 participating GPs, a total of 1,173 patients were recruited, though contributions varied widely. The top 20% of recruiters (Q5) accounted for 42.1% of all participants, while the lowest quintile (Q1) recruited just 3.2%. GPs with a doctorate degree recruited more patients (IRR = 1.45, < 0.05). Higher perceived workload was linked to increased recruitment engagement (IRR = 1.30, < 0.1). In contrast, larger practice teams were associated with lower perceived workload (OR = 0.71, < 0.1).

CONCLUSION

GP recruitment performance and perceived workload are closely linked, influenced by both individual research interest and structural support. The disproportionate recruitment burden among a small subset of GPs highlights the need for strategies to engage low recruiters and support high performers. Strengthening practice-based research networks, could help make research involvement more feasible for a wider range of GPs. : German Clinical Trials Register (DRKS; trial identifier: DRKS00013555); Date of Registration: 2017-12-07.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1186/s12875-025-02948-1.

摘要

背景

通过全科医生（GP）进行招募是初级保健试验中的一项关键挑战。了解个体、诊所和地区特征如何影响招募及感知工作量，有助于优化参与策略。本研究旨在确定AgeWell.de痴呆症预防试验中患者招募的障碍和促进因素。

方法

我们分析了参与AgeWell.de试验的全科医生的公开数据，包括他们的社会人口学特征、诊所结构及其诊所所在地的社会经济指标，以及招募和调查数据。我们使用相关分析以及单变量和多变量回归模型，从招募表现和感知工作量方面探索研究参与的决定因素。

结果

在120名参与试验的全科医生中，共招募了1173名患者，但各医生的贡献差异很大。招募量最高的20%的医生（第五分位数）占所有参与者的42.1%，而最低的五分之一（第一分位数）仅招募了3.2%。拥有博士学位的全科医生招募的患者更多（发病率比值比[IRR]=1.45，P<0.05）。较高的感知工作量与增加的招募参与度相关（IRR=1.30，P<0.1）。相比之下，规模较大的诊所团队与较低的感知工作量相关（比值比[OR]=0.71，P<0.1）。

结论

全科医生的招募表现与感知工作量密切相关，受到个人研究兴趣和结构支持的影响。一小部分全科医生承担的不成比例的招募负担凸显了吸引招募量低的医生并支持表现出色的医生的策略的必要性。加强基于诊所的研究网络，可能有助于使更多全科医生更可行地参与研究。：德国临床试验注册中心（DRKS；试验标识符：DRKS00013555）；注册日期：2017年12月7日。