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输尿管软镜检查治疗大型近端输尿管结石时粉末化与碎石术的比较:一项前瞻性随机研究

Dusting versus fragmentation for large proximal ureteral stones during flexible ureteroscopy: A prospective randomized study.

作者信息

Morsy Samer, Essam Ahmed, Nasser Islam, Elsheikh Mohamed, Rahman Sherif Abdel, Daw Kareem

机构信息

Kasr Al Ainy Hospital, Cairo University, Cairo, Egypt.

出版信息

Curr Urol. 2025 Jul;19(4):257-262. doi: 10.1097/CU9.0000000000000285. Epub 2025 May 19.

Abstract

BACKGROUND

Recent advances in endoscopic technology have empowered urologists to treat most types of stones within the urinary tract effectively. Available treatments for ureteral stones using a laser lithotripter include fragmentation, the active removal of fragments with a basket, and dusting. To date, only a few prospective randomized studies have endorsed the use of stone dusting, fragmentation, and active removal for ureteric stones.

MATERIALS AND METHODS

This randomized, prospective, comparative study was conducted in the Urology Department. Sixty patients with proximal ureteral stones from July 2019 to July 2020 were included and randomly divided into 2 groups using a random number generator program (version 2, 2015). In Group 1, the stones were fragmented into dust (n = 30), and in Group 2, lithotripsy produced extractable fragments (n = 30).

RESULTS

In this study, the Ho:YAG laser was used to dust stones at low energy and high frequency (0.4-0.6 J and 20-30 Hz). Using the Ho:YAG laser set to high energy and low frequency (1.5-2 J and 8-10 Hz), stone fragmentation was achieved. The mean stone size was 1.63 cm in Group 1 and 1.69 cm in Group 2. The stone-free rates for the dusting and fragmentation groups were 96.6% and 86.6%, respectively. Meanwhile, the mean operative time was 87.6 ± 33.6 minutes in the dusting group and 80.4 ± 28.8 minutes in the fragmentation group. There were no postoperative complications with the dusting technique, compared with a 13.3% complication rate with the fragmentation technique.

CONCLUSIONS

For proximal ureteral stones, the stone-free rates between the dusting and fragmentation procedures were comparable. Both techniques proved to be effective.

摘要

背景

内镜技术的最新进展使泌尿外科医生能够有效治疗大多数类型的尿路结石。使用激光碎石器治疗输尿管结石的现有方法包括碎石、用网篮主动取出碎片和粉末化。迄今为止,只有少数前瞻性随机研究支持对输尿管结石使用结石粉末化、碎石和主动取出方法。

材料与方法

本随机、前瞻性、对照研究在泌尿外科进行。纳入2019年7月至2020年7月的60例近端输尿管结石患者,使用随机数字生成程序(2015版第2版)随机分为2组。第1组将结石碎成粉末(n = 30),第2组碎石后产生可取出的碎片(n = 30)。

结果

在本研究中,钬激光用于低能量、高频(0.4 - 0.6 J和20 - 30 Hz)的结石粉末化。将钬激光设置为高能量、低频(1.5 - 2 J和8 - 10 Hz)可实现结石破碎。第1组结石平均大小为1.63 cm,第2组为1.69 cm。粉末化组和碎石组的无结石率分别为96.6%和86.6%。同时,粉末化组平均手术时间为87.6 ± 33.6分钟,碎石组为80.4 ± 28.8分钟。粉末化技术无术后并发症,而碎石技术的并发症发生率为13.3%。

结论

对于近端输尿管结石,粉末化和碎石方法的无结石率相当。两种技术均被证明有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61bc/12321463/4e7283e48197/curr-urol-19-257-g001.jpg

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