Suppr超能文献

钬光纤激光治疗尿路结石的疗效:系统评价结果。

Outcomes of thulium fibre laser for treatment of urinary tract stones: results of a systematic review.

机构信息

Hospital CUF Descobertas, Lisbon, Portugal.

Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.

出版信息

Curr Opin Urol. 2021 Mar 1;31(2):80-86. doi: 10.1097/MOU.0000000000000853.

Abstract

PURPOSE OF REVIEW

Lasers have become a fundamental aspect of stone treatment. Although Holmium:Yttrium-Aluminum-garnet (Ho:YAG) laser is the current gold-standard in endoscopic laser lithotripsy, there is a lot of buzz around the new thulium fibre laser (TFL). We decided to evaluate the latest data to help create an objective and evidence-based opinion about this new technology and associated clinical outcomes.

RECENT FINDINGS

Sixty full-text articles and peer-reviewed abstract presentations were included in the qualitative synthesis of this systematic review performed over the last 2 years. Current super pulsed TFL machines are capable of achieving peak powers of 500W and emit very small pulse energies of 0.025 Joules going up to 6 Joules, and capable of frequency over 2000 Hz. This makes the TFL ablate twice as fast for fragmentation, 4 times as fast for dusting, more stone dust of finer size and less retropulsion compared to the Ho:YAG laser. Because of the smaller laser fibres with the TFL, future miniaturization of instruments is also possible.

SUMMARY

Based on the review, the TFL is a potential game-changer for kidney stone disease and has a promising role in the future. However larger multicentric prospective clinical studies with long-term follow-up are needed to establish the safety and efficacy of the TFL in endourology.

摘要

目的综述:激光已经成为结石治疗的一个基本手段。虽然钬激光(Ho:YAG)是目前腔内激光碎石术的金标准,但新型掺铥光纤激光(TFL)也备受关注。我们评估了最新的数据,以帮助对这项新技术及其相关临床结果形成客观和基于证据的观点。

最新发现:在过去 2 年进行的这项系统评价的定性综合分析中,共纳入了 60 篇全文文章和同行评审的摘要报告。目前的超脉冲 TFL 机可达到 500W 的峰值功率,发射非常小的 0.025 焦耳脉冲能量,最高可达 6 焦耳,频率可超过 2000Hz。与 Ho:YAG 激光相比,这使得 TFL 的碎石速度快两倍,粉碎速度快四倍,产生的结石粉尘更小,后向推力更小。由于 TFL 采用了更小的激光光纤,未来仪器的小型化也成为可能。

总结:基于这项综述,TFL 可能是肾结石治疗的一个重大变革,在未来具有广阔的应用前景。然而,需要进行更大规模的多中心前瞻性临床研究,以确定 TFL 在腔内泌尿外科中的安全性和疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32cf/7879830/a5732ecb9c5a/couro-31-80-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验