• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

采用分期手术成功治疗极低出生体重儿巨大多发性肠气囊肿瘘：1例病例报告及文献复习

Successful treatment of giant multiple enteroatmospheric fistulas in an extremely premature infant using staged procedures. A case report and literature review.

作者信息

Alhalabi Rawan, Alsweed Ahmad, Hamud Osama, Ramaiah Sridhar M, Gupta Chetan, Shah Ubaid, Belsha Dalia, Muad Hussein, Umer Afsheen, Ba'ath Muhammad Eyad

机构信息

Pediatric Department, American Hospital Dubai, Oud Metha, Dubai, United Arab Emirates.

Pediatric Surgery Department, American Hospital Dubai, Oud Metha, Dubai, United Arab Emirates.

出版信息

J Surg Case Rep. 2025 Aug 4;2025(8):rjaf582. doi: 10.1093/jscr/rjaf582. eCollection 2025 Aug.

DOI:10.1093/jscr/rjaf582
PMID:40765637
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12319319/
Abstract

Necrotizing enterocolitis (NEC) remains a leading cause of morbidity in extremely low birth weight neonates. We report a complex surgical management of a 560 g preterm infant with NEC complicated by intestinal perforation, enteroatmospheric fistula, and prolonged open abdomen. Management included negative pressure wound therapy combined with stoma bag application, prolonged total parenteral nutrition, and delayed reconstruction using multiple anastomoses and tube stomas. Final abdominal closure was achieved with absorbable mesh and skin flaps. Despite prolonged hospitalization and multiple complications, enteral autonomy was ultimately achieved. This case highlights the challenges of managing NEC-related enteroatmospheric fistulas in extremely low birth weight infants and supports the use of negative pressure wound therapy and staged reconstruction to preserve bowel length and avoid short gut syndrome.

摘要

坏死性小肠结肠炎（NEC）仍然是极低出生体重儿发病的主要原因。我们报告了一例体重560克的早产儿坏死性小肠结肠炎的复杂外科治疗，该患儿合并肠穿孔、肠造口瘘和长期开放性腹腔。治疗措施包括负压伤口治疗联合造口袋应用、长期全胃肠外营养，以及采用多次吻合和管形造口进行延迟重建。最终使用可吸收网片和皮瓣实现了腹腔关闭。尽管住院时间长且出现多种并发症，但最终实现了肠道自主功能。该病例突出了极低出生体重儿坏死性小肠结肠炎相关肠造口瘘管理的挑战，并支持使用负压伤口治疗和分期重建以保留肠长度并避免短肠综合征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/12319319/a209612d0993/rjaf582f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/12319319/be662b212f35/rjaf582f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/12319319/ce7ed6492874/rjaf582f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/12319319/e0d37ded645a/rjaf582f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/12319319/d88a0543a857/rjaf582f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/12319319/9993b60ac9a5/rjaf582f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/12319319/afbbd6d251cc/rjaf582f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/12319319/1e675211e22b/rjaf582f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/12319319/a209612d0993/rjaf582f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/12319319/be662b212f35/rjaf582f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/12319319/ce7ed6492874/rjaf582f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/12319319/e0d37ded645a/rjaf582f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/12319319/d88a0543a857/rjaf582f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/12319319/9993b60ac9a5/rjaf582f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/12319319/afbbd6d251cc/rjaf582f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/12319319/1e675211e22b/rjaf582f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a2/12319319/a209612d0993/rjaf582f8.jpg

相似文献

1
Successful treatment of giant multiple enteroatmospheric fistulas in an extremely premature infant using staged procedures. A case report and literature review.采用分期手术成功治疗极低出生体重儿巨大多发性肠气囊肿瘘：1例病例报告及文献复习
J Surg Case Rep. 2025 Aug 4;2025(8):rjaf582. doi: 10.1093/jscr/rjaf582. eCollection 2025 Aug.
2
Slow advancement of enteral feed volumes to prevent necrotising enterocolitis in very low birth weight infants.缓慢增加肠内喂养量以预防极低出生体重儿坏死性小肠结肠炎
Cochrane Database Syst Rev. 2017 Aug 30;8(8):CD001241. doi: 10.1002/14651858.CD001241.pub7.
3
Early treatment versus expectant management of hemodynamically significant patent ductus arteriosus for preterm infants.早产儿血流动力学显著的动脉导管未闭的早期治疗与观察性管理
Cochrane Database Syst Rev. 2025 Jun 23;6(6):CD013278. doi: 10.1002/14651858.CD013278.pub3.
4
Peritoneal drainage versus laparotomy as initial treatment for surgical necrotising enterocolitis or spontaneous intestinal perforation in preterm very low birth weight infants.对于早产极低出生体重儿的外科坏死性小肠结肠炎或自发性肠穿孔，采用腹腔引流与剖腹手术作为初始治疗方法的比较
Cochrane Database Syst Rev. 2025 Jun 24;6(6):CD006182. doi: 10.1002/14651858.CD006182.pub3.
5
Ibuprofen for the treatment of patent ductus arteriosus in preterm and/or low birth weight infants.布洛芬用于治疗早产和/或低出生体重婴儿的动脉导管未闭。
Cochrane Database Syst Rev. 2008 Jan 23(1):CD003481. doi: 10.1002/14651858.CD003481.pub3.
6
Delayed introduction of progressive enteral feeds to prevent necrotising enterocolitis in very low birth weight infants.延迟引入渐进性肠内喂养以预防极低出生体重儿坏死性小肠结肠炎。
Cochrane Database Syst Rev. 2013 May 31(5):CD001970. doi: 10.1002/14651858.CD001970.pub4.
7
Delayed introduction of progressive enteral feeds to prevent necrotising enterocolitis in very low birth weight infants.延迟引入渐进性肠内喂养以预防极低出生体重儿坏死性小肠结肠炎
Cochrane Database Syst Rev. 2014;2014(12):CD001970. doi: 10.1002/14651858.CD001970.pub5. Epub 2014 Dec 1.
8
Slow advancement of enteral feed volumes to prevent necrotising enterocolitis in very low birth weight infants.缓慢增加肠内喂养量以预防极低出生体重儿坏死性小肠结肠炎
Cochrane Database Syst Rev. 2015 Oct 15(10):CD001241. doi: 10.1002/14651858.CD001241.pub6.
9
Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low birth weight infants.对早产儿或低出生体重儿的动脉导管未闭（patent ductus arteriosus），使用扑热息痛（acetaminophen，对乙酰氨基酚）。
Cochrane Database Syst Rev. 2022 Dec 15;12:CD010061. doi: 10.1002/14651858.CD010061.pub5.
10
Routine monitoring of gastric residual for prevention of necrotising enterocolitis in preterm infants.常规监测胃残余物以预防早产儿坏死性小肠结肠炎。
Cochrane Database Syst Rev. 2023 Jun 16;6(6):CD012937. doi: 10.1002/14651858.CD012937.pub3.

本文引用的文献

1
A review of chyme reinfusion: new tech solutions for age old problems.食糜再输注综述：解决老问题的新技术方案
J R Soc N Z. 2022 Sep 7;54(2):161-176. doi: 10.1080/03036758.2022.2117832. eCollection 2024.
2
Evaluating the efficacy and safety of neonatal chyme reinfusion therapy: A feasibility study using a novel medical device.评估新生儿食糜再灌注治疗的疗效和安全性：使用新型医疗器械的可行性研究。
Clin Nutr. 2024 Oct;43(10):2253-2260. doi: 10.1016/j.clnu.2024.08.016. Epub 2024 Aug 21.
3
Postoperative Necrotizing Enterocolitis Following Inguinal Hernia Repair in an Infant: Case Report and Review of the Literature.
婴儿腹股沟疝修补术后坏死性小肠结肠炎：病例报告及文献复习
Cureus. 2023 Sep 12;15(9):e45089. doi: 10.7759/cureus.45089. eCollection 2023 Sep.
4
Laparotomy versus Peritoneal Drainage as Primary Treatment for Surgical Necrotizing Enterocolitis or Spontaneous Intestinal Perforation in Preterm Neonates: A Systematic Review and Meta-Analysis.剖腹手术与腹腔引流作为早产儿外科坏死性小肠结肠炎或自发性肠穿孔的主要治疗方法：一项系统评价和荟萃分析
Children (Basel). 2023 Jul 6;10(7):1170. doi: 10.3390/children10071170.
5
Initial surgical treatment of necrotizing enterocolitis: a meta-analysis of peritoneal drainage versus laparotomy.新生儿坏死性小肠结肠炎的初始外科治疗：腹腔引流与剖腹术的荟萃分析。
Eur J Pediatr. 2022 Jul;181(7):2593-2601. doi: 10.1007/s00431-022-04454-3. Epub 2022 Apr 22.
6
Minimizing Enterostomy Complication in Neonates, Lessons Learnt from Three European Tertiary Centres.新生儿肠造口术并发症的最小化：来自三个欧洲三级医疗中心的经验教训
Children (Basel). 2022 Jan 27;9(2):162. doi: 10.3390/children9020162.
7
Chyme recycling in the management of small bowel double enterostomy in pediatric and neonatal populations: A systematic review.小儿和新生儿小肠双造口术管理中食糜再循环：系统评价。
Clin Nutr ESPEN. 2020 Jun;37:1-8. doi: 10.1016/j.clnesp.2020.03.013. Epub 2020 Apr 7.
8
Negative-Pressure Wound Therapy in Infants and Children: A Population-Based Study.负压伤口疗法在婴儿和儿童中的应用：一项基于人群的研究。
J Surg Res. 2019 Mar;235:560-568. doi: 10.1016/j.jss.2018.10.043. Epub 2018 Nov 30.
9
Early postoperative outcomes of surgery for intestinal perforation in NEC based on intestinal location of disease.基于坏死性小肠结肠炎（NEC）疾病肠道位置的肠穿孔手术早期术后结局
Medicine (Baltimore). 2018 Sep;97(39):e12234. doi: 10.1097/MD.0000000000012234.
10
Successful treatment of enteroatmospheric fistulas in combination with negative pressure wound therapy: Experience on 3 cases and literature review.肠内-大气瘘经负压伤口治疗成功治愈 3 例报告并文献复习
Int Wound J. 2018 Oct;15(5):722-730. doi: 10.1111/iwj.12916. Epub 2018 Mar 30.