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1例并发假性断肢的掌跖角化病病例及文献复习

A Case of Palmoplantar Keratodermas Complicated by Pseudoainhum and Literature Review.

作者信息

Ye Junhong, Li Wen, Yang Xianxu, Shi Yanhai, Lv Wen

机构信息

Department of Plastic Surgery and Skin Disease, Hainan Fifth People's Hospital, Haikou City, Hainan Province, People's Republic of China.

Department of Skin Disease, Qionghai People's Hospital, Qionghai City, Hainan Province, People's Republic of China.

出版信息

Clin Cosmet Investig Dermatol. 2025 Jul 31;18:1827-1831. doi: 10.2147/CCID.S534631. eCollection 2025.

DOI:10.2147/CCID.S534631
PMID:40765698
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12323793/
Abstract

A 43-year-old man who had presented diffuse plaques on both hands and feet for 10 years and constriction of the fifth digit of the right foot for 1 year was included in this case report. Diffuse hyperplastic yellow-brown plaques were observed in the palms of both hands and soles of both feet in this man. Yellowish crusting formed on the plaques. There was much white debris on the surface lesions. The fifth phalanx of the right foot was ring-shaped and narrowed, and the toe was globular. Color Doppler ultrasound examination revealed arteriosclerosis and multiple small plaques in the right lower limb vessel. An antero-posterior radiograph of the right foot showed constriction of the fifth phalanx. The man was diagnosed with palmoplantar keratodermas complicated by pseudoainhum.

摘要

本病例报告纳入了一名43岁男性,其双手和双足出现弥漫性斑块10年,右足第五趾缩窄1年。该男性双手掌和双足底可见弥漫性增生性黄褐色斑块。斑块上形成淡黄色结痂。表面皮损有大量白色碎屑。右足第五趾骨呈环形且变窄,趾端呈球状。彩色多普勒超声检查显示右下肢血管动脉硬化并伴有多个小斑块。右足正位X线片显示第五趾骨缩窄。该男性被诊断为掌跖角化病并发假阿洪病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e617/12323793/1c8253fdc65a/CCID-18-1827-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e617/12323793/8e5951f4e645/CCID-18-1827-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e617/12323793/f96ae951868d/CCID-18-1827-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e617/12323793/1c8253fdc65a/CCID-18-1827-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e617/12323793/8e5951f4e645/CCID-18-1827-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e617/12323793/f96ae951868d/CCID-18-1827-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e617/12323793/1c8253fdc65a/CCID-18-1827-g0003.jpg

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本文引用的文献

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Palmoplantar keratoderma, pseudo-ainhum and knuckle pads in an African patient: A case report.一名非洲患者的掌跖角化病、假自发性断指和指节垫:病例报告
SAGE Open Med Case Rep. 2023 Oct 14;11:2050313X231204197. doi: 10.1177/2050313X231204197. eCollection 2023.
2
Exploring Pseudoainhum in Camisa syndrome.探索卡米萨综合征中的自发性断指症
Clin Case Rep. 2021 Oct 23;9(10):e04995. doi: 10.1002/ccr3.4995. eCollection 2021 Oct.
3
First report of Mal de Meleda with pseudo-ainhum treated with gabapentin in a 17-year-old Chinese girl.
17岁中国女孩患伴有假自发性断指症的梅勒达病,用加巴喷丁治疗的首例报告。
Australas J Dermatol. 2021 Aug;62(3):e466-e468. doi: 10.1111/ajd.13625. Epub 2021 May 13.
4
Nagashima-Type Palmoplantar Keratosis: Clinical Characteristics, Genetic Characterization, and Clinical Management.Nagashima 型掌跖角化病:临床特征、遗传特征及临床管理。
Biomed Res Int. 2021 Jan 27;2021:8841994. doi: 10.1155/2021/8841994. eCollection 2021.
5
Surgical management of pseudoainhum in loricrin keratoderma.loricrin角化病中假性断肢的手术治疗
JAAD Case Rep. 2020 Jul 28;6(10):1012-1015. doi: 10.1016/j.jdcr.2020.07.029. eCollection 2020 Oct.
6
Unilateral Pseudo-Ainhum in Liver Cirrhosis.肝硬化中的单侧假性阿洪病
Open Access Maced J Med Sci. 2019 Sep 10;7(18):3013-3014. doi: 10.3889/oamjms.2019.681. eCollection 2019 Sep 30.
7
Palmoplantar keratosis and raindrop pigmentation in chronic arsenicosis.慢性砷中毒中的掌跖角化病和雨滴状色素沉着
QJM. 2020 Aug 1;113(8):584-585. doi: 10.1093/qjmed/hcz309.
8
Resolution of pseudoainhum with acitretin therapy in a patient with palmoplantar keratoderma and congenital alopecia.一名患有掌跖角化病和先天性脱发的患者使用阿维A治疗后假性断肢症状得到缓解。
JAAD Case Rep. 2019 Feb 12;5(3):219-221. doi: 10.1016/j.jdcr.2018.12.004. eCollection 2019 Mar.
9
Congenital linear porokeratosis with pseudoainhum.先天性线状汗孔角化症伴假性断肢症
Eur J Dermatol. 2010 Nov-Dec;20(6):817-8. doi: 10.1684/ejd.2010.1068. Epub 2010 Oct 18.
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