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5%米诺地尔与富血小板血浆疗法治疗雄激素性脱发的疗效——一项回顾性研究

Efficiency of 5% Minoxidil and Platelet-rich Plasma Therapy in Androgenetic Alopecia - A Retrospective Study.

作者信息

Dubey Chanda, Jaiswal Pooja, Goyal Rohit, Ramalingam Karthikeyan, Kalita Sangita, Akhter Javed

机构信息

Department of Oral and Maxillofacial Surgery, Maharaja Ganga Singh Dental College and Research Centre, Sri Ganganagar, Rajasthan, India.

Department of Oral Pathology and Microbiology, Malla Reddy Institute of Dental Sciences, Malla Reddy Vishwavidyapeeth, Hyderabad, Telangana, India.

出版信息

Ann Maxillofac Surg. 2025 Jan-Jun;15(1):61-66. doi: 10.4103/ams.ams_168_24. Epub 2025 Mar 7.

Abstract

INTRODUCTION

Androgenetic alopecia (AA) is the most common reason for hair loss in men. Minoxidil therapy has been the gold standard. Platelet-rich plasma (PRP) therapy has shown promising results. This study aimed to analyze the hospital data for the clinical efficiency of PRP therapy in comparison to topical minoxidil among AA.

MATERIALS AND METHODS

This retrospective single-centre cohort study analysed the patients treated in the Department of Oral and Maxillofacial Surgery. Sixty-two case records with AA were retrieved, and their treatment options were analysed. Retrieved data were analysed using SPSS v26.0.

RESULTS

Forty complete case records were included for detailed comparison with 20 records in each group of PRP and minoxidil. Twelve had discontinued therapy and analysis included 28 records. Both groups had 6 months of follow-up data checked for a standardised hair growth questionnaire, global photography, hair pull test and patient satisfaction ratings.

DISCUSSION

We observed in our study that PRP therapy was efficient for AA. Minoxidil therapy topically may be advantageously replaced with the PRP injection.

摘要

引言

雄激素性脱发(AA)是男性脱发的最常见原因。米诺地尔疗法一直是金标准。富血小板血浆(PRP)疗法已显示出有前景的结果。本研究旨在分析医院数据,以比较PRP疗法与局部米诺地尔治疗AA的临床疗效。

材料与方法

这项回顾性单中心队列研究分析了口腔颌面外科治疗的患者。检索了62例AA病例记录,并分析了他们的治疗选择。使用SPSS v26.0分析检索到的数据。

结果

纳入40份完整病例记录进行详细比较,PRP组和米诺地尔组各20份记录。12例已停止治疗,分析包括28份记录。两组均有6个月的随访数据,检查标准化头发生长问卷、整体照片、拔发试验和患者满意度评分。

讨论

我们在研究中观察到PRP疗法对AA有效。局部米诺地尔疗法可能有利地被PRP注射所取代。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84e/12321180/6e22258d0b22/AMS-15-61-g001.jpg

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