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恒河猴输精管切除术I. 手术技术与大体观察

Vasectomy in rhesus monkeys I. Surgical techniques and gross observations.

作者信息

Harrison R M, Domingue G J, Heidger P M, Roberts J A, Schlegel J U

出版信息

Urology. 1977 Jun;9(6):639-44. doi: 10.1016/0090-4295(77)90310-7.

Abstract

Vasectomy and vaso-occlusion techniques were used in 47 male rhesus monkeys to maximize and minimize the amount of sperm allowed to escape from the vas into surrounding tissues for up to seventy-two weeks postoperatively. Body weight changes and blood clinical data indicated that the general health of all the monkeys remained good. Normal seasonal changes in body weights and testicular volumes suggested that there were no disturbances to the endocrine system and that the monkeys remained responsive to seasonal environmental stimuli. Vasectomy appears to cause no short-term deleterious effects in the rhesus monkeys, based on observations made during the seventy-two weeks that these monkeys were study after vasectomy. This conclusion agrees with the findings of other investigators.

摘要

在47只雄性恒河猴身上采用了输精管切除术和输精管阻塞技术,以在术后长达72周的时间内,使从输精管进入周围组织的精子数量最大化和最小化。体重变化和血液临床数据表明,所有猴子的总体健康状况良好。体重和睾丸体积的正常季节性变化表明,内分泌系统未受干扰,猴子对季节性环境刺激仍有反应。根据对这些猴子输精管切除术后72周的观察,输精管切除术似乎不会对恒河猴产生短期有害影响。这一结论与其他研究者的发现一致。

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