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恒河猴输精管切除术。III. 睾丸形态学的光镜研究。

Vasectomy in rhesus monkeys. III. Light microscopic studies of testicular morphology.

作者信息

Heidger P M, Roberts J A, Chapman E S, Domingue G J, Harrison R M, Schlegel J U

出版信息

Urology. 1978 Feb;11(2):148-52. doi: 10.1016/0090-4295(78)90094-8.

DOI:10.1016/0090-4295(78)90094-8
PMID:415398
Abstract

Rhesus monkeys were randomly assigned to undergo various surgical procedures. The animals were followed from one to sixty-six weeks postvasectomy, at which time they were sacrificed and their tissues prepared for light and electron microscopy. Vasectomy in the rhesus monkey, as in certain other species, appears to be a procedure not attended with widespread testicular atrophy or histologic evidence of impaired spermatogenic potential utilizing the procedures and postoperative periods studied. Why certain animals exhibited focal degenerative changes is unclear; perhaps a certain population, yet to be defined, is more sensitive to such procedures, resulting in testicular alterations. It is important that such a population and such changes be defined to predict more accurately the possibility of successful vasovasostomy and reestablishment of fertility.

摘要

恒河猴被随机分配接受各种外科手术。在输精管切除术后1至66周对这些动物进行跟踪观察,此时将它们处死,并准备其组织用于光学显微镜和电子显微镜检查。与某些其他物种一样,恒河猴的输精管切除术似乎是一种不会导致广泛睾丸萎缩或在所用手术及术后观察期内出现生精潜能受损组织学证据的手术。某些动物为何会出现局灶性退行性变化尚不清楚;也许尚未明确的某一群体对这类手术更为敏感,从而导致睾丸改变。明确这样一个群体及其变化对于更准确地预测输精管吻合术成功及恢复生育能力的可能性很重要。

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