Desiatnichenko K S, Leont'ev V K
Vopr Med Khim. 1977 Mar-Apr;23(2):210-5.
Three groups of proteins, distinguished by solubility in acidic and neutral media, were found in enamel. Molecular weight of the major part of proteins, insoluble at neutral pH, was about 20000; these proteins readily interacted with Ca2+, developing tri- and tetrameric molecules. High molecular enamel protein reversibly disaggregated after removing of Ca2+ by various methods. The insoluble protein had a highly regular structure. Mineralization of the protein appears to occur due to development of bonds between Ca2 and some amino acid residues.
在牙釉质中发现了三类蛋白质，它们根据在酸性和中性介质中的溶解性来区分。在中性pH值下不溶的蛋白质的主要部分分子量约为20000；这些蛋白质很容易与Ca2+相互作用，形成三聚体和四聚体分子。通过各种方法去除Ca2+后，高分子量牙釉质蛋白会可逆地解聚。不溶性蛋白质具有高度规则的结构。蛋白质的矿化似乎是由于Ca2+与一些氨基酸残基之间形成了键。
