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目前的量表是否足以评估肿瘤细胞减灭术和腹腔内热灌注化疗后的生活质量?

Are current scales adequate for assessing quality of life after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy?

作者信息

Demirli Atici Semra, Canda Aras Emre, Terzi Mustafa Cem

机构信息

Department of General Surgery, Acibadem Kent Hospital, Izmir 35620, Türkiye.

KRC Clinic for Colorectal Surgery and Peritoneal Surface Malignancies, Izmir 35220, Türkiye.

出版信息

World J Clin Cases. 2025 Aug 6;13(22):105884. doi: 10.12998/wjcc.v13.i22.105884.

DOI:10.12998/wjcc.v13.i22.105884
PMID:40771737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12188830/
Abstract

Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are complex surgical procedures that are often used to treat advanced cancers of the abdominal cavity with peritoneal metastasis. Although these treatments can be lifesaving, patients often experience a significant decrease in their overall quality of life (QoL), especially in the early stages of recovery, owing to the physical burden of surgery and the effects of chemotherapy. Many traditional QoL questionnaires have been used to measure CRS and HIPEC. However, these classical current QoL assessment tools often fail to capture the unique challenges faced by this population, including bowel dysfunction, stoma-related distress, and long-term survivorship issues. Therefore, additional parameters that assess bowel function and stoma opening status and especially patient-reported outcome measures would be useful in QoL measurements to provide a more detailed understanding of recovery and general well-being in these patients.

摘要

减瘤手术(CRS)和腹腔热灌注化疗(HIPEC)是复杂的外科手术,常用于治疗伴有腹膜转移的晚期腹腔癌症。尽管这些治疗可以挽救生命,但由于手术的身体负担和化疗的影响,患者的总体生活质量(QoL)通常会显著下降,尤其是在恢复的早期阶段。许多传统的生活质量问卷已被用于评估CRS和HIPEC。然而,这些经典的当前生活质量评估工具往往无法捕捉该人群面临的独特挑战,包括肠道功能障碍、造口相关困扰和长期生存问题。因此,在生活质量测量中,评估肠道功能和造口开放状态的额外参数,尤其是患者报告的结局指标,将有助于更详细地了解这些患者的恢复情况和总体健康状况。

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Patient Perspectives of Fertility Following Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy: An Opportunity for Improved Perioperative Counseling.接受细胞减灭术联合热灌注化疗后患者对生育能力的看法:改善围手术期咨询的契机
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