Ezell Susan
From University of Arkansas, Fayetteville, Arkansas.
J Adv Pract Oncol. 2025 Jul 1;16(4):137-142. doi: 10.6004/jadpro.2025.16.4.2. eCollection 2025 Jul.
Indications for the use of cytomegalovirus (CMV)-neg-ative and irradiated blood products (IRBP) are not standardized and are often poorly understood by providers. This project evaluated the use of a transfusion algorithm in an outpatient oncology clinic to reduce the risk of transfusion-associated graft-vs.-host disease (TA-GVHD) and eliminate the improper use of CMV-negative and irradiated blood products.
The aim of this project was to increase the correct use of CMV-negative and irradiated blood products at an outpatient oncology clinic by establishing a transfusion algorithm, to evaluate the effectiveness of clinical transfusion algorithms on the use of specialty blood products, and to educate providers on TA-GVHD.
This quasi-experimental project compared 12 weeks of transfusion data before the implementation of a transfusion algorithm to 12 weeks of transfusion data after the algorithm was introduced. A preand post-test survey measured the satisfaction and the impact of the education.
The transfusion algorithm resulted in a clinically significant increase in the correct use of both CMV-negative and irradiated blood products at an outpatient oncology clinic. The education in-services provided to staff about TA-GVHD and the indications for irradiated blood product resulted in a significant increase in provider knowledge on ordering specialty blood products.
巨细胞病毒（CMV）阴性且经过辐照的血液制品（IRBP）的使用指征未标准化，且医护人员对此往往了解不足。本项目评估了在门诊肿瘤诊所使用输血算法，以降低输血相关移植物抗宿主病（TA-GVHD）的风险，并消除CMV阴性和辐照血液制品的不当使用情况。
本项目的目的是通过建立输血算法，提高门诊肿瘤诊所CMV阴性和辐照血液制品的正确使用率，评估临床输血算法对特殊血液制品使用的有效性，并对医护人员进行TA-GVHD相关教育。
这个准实验项目将输血算法实施前12周的输血数据与引入算法后12周的输血数据进行了比较。一项前后测试调查衡量了教育的满意度和影响。
输血算法使门诊肿瘤诊所CMV阴性和辐照血液制品的正确使用率在临床上显著提高。向工作人员提供的关于TA-GVHD和辐照血液制品指征的在职教育，使医护人员在订购特殊血液制品方面的知识显著增加。
