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耶尔森菌不只是引发鼠疫:一例由小肠结肠炎耶尔森菌引起的耶尔森菌病病例报告。

Yersinia Is Not Just the Plague: A Case Report of Yersiniosis Caused by Yersinia enterocolitica.

作者信息

Hashmi Shahnawaz, Majumder Sunrit, Gillani Zamad, Ali Mariyam

机构信息

Internal Medicine, South Tees NHS Foundation Trust, Middlesbrough, GBR.

Respiratory Medicine, South Tees NHS Foundation Trust, Middlesbrough, GBR.

出版信息

Cureus. 2025 Jul 6;17(7):e87381. doi: 10.7759/cureus.87381. eCollection 2025 Jul.

Abstract

Yersinia enterocolitica is a Gram-negative bacterium that typically causes self-limiting gastrointestinal infections but can sometimes lead to systemic complications, particularly in immunocompromised hosts. This report describes a rare case of a 60-year-old farmer who developed enteric bacteremia, renal impairment, and pulmonary manifestations, likely due to the consumption of undercooked pork. Despite lacking common predisposing factors, the patient presented with a sore throat, joint pain, abdominal discomfort, and a characteristic erythematous rash. Extensive diagnostic workup, including blood cultures and autoimmune screening, yielded negative results. However, stool culture eventually identified Y. enterocolitica as the causative agent. The patient experienced worsening kidney function, respiratory distress, and significant abdominal findings on imaging, prompting consultations across multiple specialties. Treatment with doxycycline and amoxicillin led to clinical improvement, and the patient's renal function returned to baseline. This case highlights the potential for Y. enterocolitica to cause rare and severe extra-intestinal manifestations, including pulmonary involvement, in an immunocompetent host, underscoring the importance of considering this pathogen in differential diagnoses of systemic infections.

摘要

小肠结肠炎耶尔森菌是一种革兰氏阴性菌,通常引起自限性胃肠道感染,但有时可导致全身并发症,尤其是在免疫功能低下的宿主中。本报告描述了一例罕见病例,一名60岁的农民因食用未煮熟的猪肉而发生肠道菌血症、肾功能损害和肺部表现。尽管缺乏常见的易感因素,但患者出现了喉咙痛、关节痛、腹部不适和特征性红斑皮疹。广泛的诊断检查,包括血培养和自身免疫筛查,结果均为阴性。然而,粪便培养最终确定小肠结肠炎耶尔森菌为病原体。患者肾功能恶化、呼吸窘迫,影像学检查发现明显的腹部病变,促使多个专科进行会诊。使用强力霉素和阿莫西林治疗后临床症状改善,患者肾功能恢复至基线水平。该病例突出了小肠结肠炎耶尔森菌在免疫功能正常的宿主中引起罕见和严重肠外表现(包括肺部受累)的可能性,强调了在全身感染的鉴别诊断中考虑这种病原体的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3bc/12326207/0bb6f95ab3d6/cureus-0017-00000087381-i01.jpg

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