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冲动性与酒精使用概况:揭示人格、认知特征及《精神疾病诊断与统计手册》诊断结果

Profiles of impulsivity and alcohol use: Unveiling personality, cognitive traits, and DSM diagnoses.

作者信息

Lau Chloe, Downie Danielle, Bagby R Michael, Pollock Bruce G, Ruocco Anthony C, Quilty Lena C

机构信息

Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

Department of Psychiatry, Schulich Medicine and Dentistry, Western University, London, Ontario, Canada.

出版信息

Alcohol Clin Exp Res (Hoboken). 2025 Sep;49(9):2049-2063. doi: 10.1111/acer.70116. Epub 2025 Aug 7.

Abstract

BACKGROUND

Impulsivity is closely associated with alcohol use, but limited research has explored distinct latent profiles encompassing impulsivity traits and alcohol use disorder symptoms.

METHODS

This study used latent profile analysis (LPA) to investigate these patterns among 201 adult outpatients (50% female, 50% male) from a tertiary care setting. Participants completed self-reported measures such as the Alcohol Use Disorders Identification Test (AUDIT), Impaired Control Scale, and UPPS-P Impulsivity Scale, as well as performance-based tasks like the Probability Reward Task (PRT) and Stop Signal Reaction Time Task.

RESULTS

LPA identified three profiles using AUDIT, impaired control, and UPPS-P: (1) Low-Risk Profile-characterized by low levels of alcohol use disorder (AUD) symptoms and impulsivity; (2) Emotionally Reactive Profile-characterized by elevated impulsivity with low AUD symptoms; and (3) High-Risk Profile-characterized by elevated levels of both AUD symptoms and impulsivity. ANCOVA results revealed that Emotionally Reactive individuals scored higher on neuroticism, negative affectivity, and psychoticism and lower on conscientiousness compared to the Low-Risk group. Both Emotionally Reactive and High-Risk groups showed lower agreeableness, antagonism, and disinhibition relative to the Low-Risk group. On cognitive tasks, the Low-Risk group outperformed the High-Risk group in PRT accuracy and discriminability, while Emotionally Reactive and Low-Risk groups showed similar advantages over High Risk.

CONCLUSIONS

These findings reveal distinct personality and cognitive profiles linked to reward and control processes, informing tailored interventions for impulsivity and alcohol-related harms.

摘要

背景

冲动性与酒精使用密切相关,但探索包含冲动性特质和酒精使用障碍症状的不同潜在特征的研究有限。

方法

本研究使用潜在特征分析(LPA)来调查来自三级医疗机构的201名成年门诊患者(50%为女性,50%为男性)中的这些模式。参与者完成了自我报告测量,如酒精使用障碍识别测试(AUDIT)、控制受损量表和UPPS-P冲动量表,以及基于表现的任务,如概率奖励任务(PRT)和停止信号反应时间任务。

结果

LPA使用AUDIT、控制受损和UPPS-P识别出三种特征:(1)低风险特征——以低水平的酒精使用障碍(AUD)症状和冲动性为特征;(2)情绪反应性特征——以高冲动性和低AUD症状为特征;(3)高风险特征——以AUD症状和冲动性水平升高为特征。协方差分析结果显示,与低风险组相比,情绪反应性个体在神经质、消极情感和精神质方面得分更高,在尽责性方面得分更低。情绪反应性组和高风险组在宜人性、敌对性和去抑制方面相对于低风险组均较低。在认知任务上,低风险组在PRT准确性和辨别力方面优于高风险组,而情绪反应性组和低风险组相对于高风险组表现出类似的优势。

结论

这些发现揭示了与奖励和控制过程相关的不同人格和认知特征,为针对冲动性和酒精相关危害的量身定制干预提供了依据。

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