Abdel-Salam Mahmoud, Houssein Essam H, Emam Marwa M, Samee Nagwan Abdel, Gharehchopogh Farhad Soleimanian, Bacanin Nebojsa
Faculty of Computer and Information Science, Mansoura University, Mansoura, 35516, Egypt.
Faculty of Computers and Information, Minia University, Minia, Egypt; Minia National University, Minia, Egypt.
Comput Biol Med. 2025 Sep;196(Pt C):110835. doi: 10.1016/j.compbiomed.2025.110835. Epub 2025 Aug 6.
Intracerebral hemorrhage (ICH) is a life-threatening condition caused by bleeding in the brain, with high mortality rates, particularly in the acute phase. Accurate diagnosis through medical image segmentation plays a crucial role in early intervention and treatment. However, existing segmentation methods, such as region-growing, clustering, and deep learning, face significant limitations when applied to complex images like ICH, especially in multi-threshold image segmentation (MTIS). As the number of thresholds increases, these methods often become computationally expensive and exhibit degraded segmentation performance. To address these challenges, this paper proposes an Elite-Adaptive-Turbulent Hiking Optimization Algorithm (EATHOA), an enhanced version of the Hiking Optimization Algorithm (HOA), specifically designed for high-dimensional and multimodal optimization problems like ICH image segmentation. EATHOA integrates three novel strategies including Elite Opposition-Based Learning (EOBL) for improving population diversity and exploration, Adaptive k-Average-Best Mutation (AKAB) for dynamically balancing exploration and exploitation, and a Turbulent Operator (TO) for escaping local optima and enhancing the convergence rate. Extensive experiments were conducted on the CEC2017 and CEC2022 benchmark functions to evaluate EATHOA's global optimization performance, where it consistently outperformed other state-of-the-art algorithms. The proposed EATHOA was then applied to solve the MTIS problem in ICH images at six different threshold levels. EATHOA achieved peak values of PSNR (34.4671), FSIM (0.9710), and SSIM (0.8816), outperforming recent methods in segmentation accuracy and computational efficiency. These results demonstrate the superior performance of EATHOA and its potential as a powerful tool for medical image analysis, offering an effective and computationally efficient solution for the complex challenges of ICH image segmentation.
脑出血(ICH)是一种由脑内出血引起的危及生命的病症,死亡率很高,尤其是在急性期。通过医学图像分割进行准确诊断在早期干预和治疗中起着至关重要的作用。然而,现有的分割方法,如区域生长、聚类和深度学习,在应用于像ICH这样的复杂图像时面临重大限制,特别是在多阈值图像分割(MTIS)中。随着阈值数量的增加,这些方法通常计算成本高昂且分割性能下降。为了应对这些挑战,本文提出了一种精英自适应湍流徒步优化算法(EATHOA),它是徒步优化算法(HOA)的增强版本,专门为像ICH图像分割这样的高维和多模态优化问题设计。EATHOA集成了三种新颖的策略,包括用于提高种群多样性和探索能力的基于精英对抗学习(EOBL)、用于动态平衡探索和利用的自适应k平均最佳变异(AKAB)以及用于逃离局部最优并提高收敛速度的湍流算子(TO)。在CEC2017和CEC2022基准函数上进行了广泛的实验,以评估EATHOA的全局优化性能,结果表明它始终优于其他现有先进算法。然后将提出的EATHOA应用于解决六个不同阈值水平的ICH图像中的MTIS问题。EATHOA实现了峰值PSNR(34.4671)、FSIM(0.9710)和SSIM(0.8816),在分割精度和计算效率方面优于最近的方法。这些结果证明了EATHOA的卓越性能及其作为医学图像分析强大工具的潜力,为ICH图像分割的复杂挑战提供了一种有效且计算高效的解决方案。