注定失败：慢性肾病中的疲惫血小板 - Suppr

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Primed to Fail: Exhausted Platelets in Chronic Kidney Disease.

作者信息

Roweth Harvey G

机构信息

School of Biological Sciences, University of Reading, Reading, United Kingdom, RG6 6UB.

出版信息

JACC Basic Transl Sci. 2025 Aug 6;10(9):101358. doi: 10.1016/j.jacbts.2025.101358.

DOI:10.1016/j.jacbts.2025.101358

PMID:40774016

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12346061/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df18/12346061/dbc97d1e367c/ga1.jpg

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本文引用的文献

Impaired Secondary Platelet Response in Chronic Kidney Disease as a Consequence of Prior Platelet Activation.

JACC Basic Transl Sci. 2025 Aug 5;10(9):101355. doi: 10.1016/j.jacbts.2025.101355.

Platelets in Hemostasis, Thrombosis, and Inflammation After Major Trauma.

Arterioscler Thromb Vasc Biol. 2024 Mar;44(3):545-557. doi: 10.1161/ATVBAHA.123.318801. Epub 2024 Jan 18.

Platelet dysfunction and thrombus instability in flow conditions in patients with severe COVID-19.

Thromb Res. 2023 Jan;221:137-148. doi: 10.1016/j.thromres.2022.11.004. Epub 2022 Nov 8.

Effects of aspirin on cardiovascular outcomes in patients with chronic kidney disease.

Kidney Int. 2023 Feb;103(2):403-410. doi: 10.1016/j.kint.2022.09.023. Epub 2022 Oct 27.

Aspirin to target arterial events in chronic kidney disease (ATTACK): study protocol for a multicentre, prospective, randomised, open-label, blinded endpoint, parallel group trial of low-dose aspirin vs. standard care for the primary prevention of cardiovascular disease in people with chronic kidney disease.

Trials. 2022 Apr 21;23(1):331. doi: 10.1186/s13063-022-06132-z.

Antiplatelet agents for chronic kidney disease.

Cochrane Database Syst Rev. 2022 Feb 28;2(2):CD008834. doi: 10.1002/14651858.CD008834.pub4.

Platelet Function in CKD: A Systematic Review and Meta-Analysis.

J Am Soc Nephrol. 2021 Jul;32(7):1583-1598. doi: 10.1681/ASN.2020101440. Epub 2021 May 3.

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Primed to Fail: Exhausted Platelets in Chronic Kidney Disease.

作者信息

Roweth Harvey G

机构信息

School of Biological Sciences, University of Reading, Reading, United Kingdom, RG6 6UB.

出版信息

JACC Basic Transl Sci. 2025 Aug 6;10(9):101358. doi: 10.1016/j.jacbts.2025.101358.

DOI:10.1016/j.jacbts.2025.101358

PMID:40774016

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12346061/

Abstract

摘要

相似文献

Primed to Fail: Exhausted Platelets in Chronic Kidney Disease.

JACC Basic Transl Sci. 2025 Aug 6;10(9):101358. doi: 10.1016/j.jacbts.2025.101358.

Platelets, inflammation, and purinergic receptors in chronic kidney disease.

Kidney Int. 2024 Sep;106(3):392-399. doi: 10.1016/j.kint.2024.03.033. Epub 2024 May 29.

Impaired Secondary Platelet Response in Chronic Kidney Disease as a Consequence of Prior Platelet Activation.

JACC Basic Transl Sci. 2025 Aug 5;10(9):101355. doi: 10.1016/j.jacbts.2025.101355.

Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid antibodies.

Cochrane Database Syst Rev. 2018 Jul 13;7(7):CD012534. doi: 10.1002/14651858.CD012534.pub2.

Tetraspanin CD37 regulates platelet hyperreactivity and thrombosis.

Cardiovasc Res. 2025 Jun 12;121(6):943-956. doi: 10.1093/cvr/cvaf051.

Pathogen-reduced platelets for the prevention of bleeding.

Cochrane Database Syst Rev. 2017 Jul 30;7(7):CD009072. doi: 10.1002/14651858.CD009072.pub3.

Pathogen-reduced platelets for the prevention of bleeding.

Cochrane Database Syst Rev. 2013 Mar 28(3):CD009072. doi: 10.1002/14651858.CD009072.pub2.

Pre-activated lyophilized platelets show non-inferior hemostatic effect compared with fresh platelets in rabbits with traumatic bleeding and shock.

Platelets. 2025 Dec;36(1):2542767. doi: 10.1080/09537104.2025.2542767. Epub 2025 Aug 7.

Non-steroidal anti-inflammatory drugs and acetylsalicylic acid increase the risk of complications of diverticular disease: a meta-analysis of case-control and cohort studies.

Int J Colorectal Dis. 2022 Mar;37(3):521-529. doi: 10.1007/s00384-021-04088-1. Epub 2022 Jan 30.

Role of platelets and NETs in arterial thrombosis.

Naunyn Schmiedebergs Arch Pharmacol. 2025 Feb 24. doi: 10.1007/s00210-025-03921-6.

本文引用的文献

Impaired Secondary Platelet Response in Chronic Kidney Disease as a Consequence of Prior Platelet Activation.

JACC Basic Transl Sci. 2025 Aug 5;10(9):101355. doi: 10.1016/j.jacbts.2025.101355.

Platelets in Hemostasis, Thrombosis, and Inflammation After Major Trauma.

Arterioscler Thromb Vasc Biol. 2024 Mar;44(3):545-557. doi: 10.1161/ATVBAHA.123.318801. Epub 2024 Jan 18.

Platelet dysfunction and thrombus instability in flow conditions in patients with severe COVID-19.

Thromb Res. 2023 Jan;221:137-148. doi: 10.1016/j.thromres.2022.11.004. Epub 2022 Nov 8.

Effects of aspirin on cardiovascular outcomes in patients with chronic kidney disease.

Kidney Int. 2023 Feb;103(2):403-410. doi: 10.1016/j.kint.2022.09.023. Epub 2022 Oct 27.

Trials. 2022 Apr 21;23(1):331. doi: 10.1186/s13063-022-06132-z.

Antiplatelet agents for chronic kidney disease.

Cochrane Database Syst Rev. 2022 Feb 28;2(2):CD008834. doi: 10.1002/14651858.CD008834.pub4.

Platelet Function in CKD: A Systematic Review and Meta-Analysis.

J Am Soc Nephrol. 2021 Jul;32(7):1583-1598. doi: 10.1681/ASN.2020101440. Epub 2021 May 3.