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白色念珠菌活跃蛋白水解培养物细胞外抗原的血清学诊断价值(免疫扩散试验)

Serodiagnostic value of extracellular antigens of an actively proteolysing culture of Candida albicans (immunodiffusion-test).

作者信息

Staib F, Mishra S K, Abel T

出版信息

Zentralbl Bakteriol Orig A. 1977 Jun;238(2):284-7.

PMID:407744
Abstract

Cell-free, dialysed and concentrated culture filtrate of a Candida albicans strain, after proteolysis in serum-protein medium (bovine albumine), and after growth in Sabouraud glucose broth (for comparison) were used as antigens for the detection of precipitating antibodies in 558 samples of serum originating from defined groups of patients and healthy persons serving as controls. The differing distribution of antibodies against these two antigens as observed in the various groups of our patients calls for further studies of such antigens on the basis of proteolysis within the serodiagnostics of Candida albicans-mycoses.

摘要

白色念珠菌菌株的无细胞、透析浓缩培养滤液,经血清蛋白培养基(牛白蛋白)中的蛋白水解后,以及在沙氏葡萄糖肉汤中生长后(用于比较),用作抗原,检测来自特定患者组和作为对照的健康人的558份血清样本中的沉淀抗体。在我们不同患者组中观察到的针对这两种抗原的抗体分布差异,要求在白色念珠菌真菌病血清诊断中基于蛋白水解对这类抗原进行进一步研究。

相似文献

1
Serodiagnostic value of extracellular antigens of an actively proteolysing culture of Candida albicans (immunodiffusion-test).白色念珠菌活跃蛋白水解培养物细胞外抗原的血清学诊断价值(免疫扩散试验)
Zentralbl Bakteriol Orig A. 1977 Jun;238(2):284-7.
2
[Comparison of immunodiffusion and counterimmunoelectrophoresis for the detection of precipitating antibodies against Candida and Aspergillus antigens].免疫扩散法与对流免疫电泳法检测抗念珠菌和曲霉菌抗原沉淀抗体的比较
Mycoses. 1994;37 Suppl 1:79-83.
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Efficacy of counterimmunoelectrophoresis in the detection of fungal antibodies in allergic bronchopulmonary mycoses.对流免疫电泳在检测变应性支气管肺真菌病中真菌抗体的效能
Zentralbl Bakteriol A. 1980;247(4):537-42.
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[The quantitative immunochemical determination of specific antibodies against Candida albicans within the scope of immunological testing in the malignant melanoma (author's transl)].在恶性黑色素瘤免疫检测范围内对白色念珠菌特异性抗体进行定量免疫化学测定(作者译)
Arch Geschwulstforsch. 1980;50(5):463-7.
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Evaluation of the antigen specific to the mycelial phase of Candida albicans in the serodiagnosis of candidiasis.白色念珠菌菌丝相特异性抗原在念珠菌病血清诊断中的评估。
Tohoku J Exp Med. 1977 Dec;123(4):395-6. doi: 10.1620/tjem.123.395.
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Diagnosis of systemic candidosis by immunodiffusion test with locally prepared antigen.使用本地制备的抗原通过免疫扩散试验诊断全身性念珠菌病。
J Med Assoc Thai. 1989 Aug;72(8):436-40.
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[Electroimmunoprecipitation for the determination of precipitating antibodies in Candida mycoses--a comparison with other serological investigation methods].[用于测定念珠菌病中沉淀抗体的电免疫沉淀法——与其他血清学检测方法的比较]
Mykosen. 1975 Sep;18(9):367-73.
8
[Serodiagnosis of candidiasis].[念珠菌病的血清学诊断]
Nihon Rinsho. 1990 Feb;48 Suppl:381-4.
9
Evaluation of the antigen from chlamydospores of Candida albicans in the serodiagnosis of candidiasis.白色念珠菌厚壁孢子抗原在念珠菌病血清学诊断中的评估。
Mycopathologia. 1982 Mar 19;77(3):159-63. doi: 10.1007/BF00518801.
10
[The quantitative immunochemical determination of Candida albicans-specific antibodies (author's transl)].白色念珠菌特异性抗体的定量免疫化学测定(作者译)
Dermatol Monatsschr. 1979 Jan;165(1):13-7.

引用本文的文献

1
Competitive binding inhibition enzyme-linked immunosorbent assay that uses the secreted aspartyl proteinase of Candida albicans as an antigenic marker for diagnosis of disseminated candidiasis.竞争性结合抑制酶联免疫吸附测定,该测定使用白色念珠菌分泌的天冬氨酸蛋白酶作为抗原标记物来诊断播散性念珠菌病。
Clin Diagn Lab Immunol. 2003 Sep;10(5):835-48. doi: 10.1128/cdli.10.5.835-848.2003.
2
Apparent extracellular glycoprotein turnover product from Candida albicans.白色念珠菌明显的细胞外糖蛋白周转产物。
Mycopathologia. 1984 May 30;86(2):65-70. doi: 10.1007/BF00436488.
3
New developments in the diagnosis of opportunistic fungal infection.
机会性真菌感染诊断的新进展。
Eur J Clin Microbiol. 1986 Aug;5(4):379-88. doi: 10.1007/BF02075691.