机会性真菌感染诊断的新进展。
New developments in the diagnosis of opportunistic fungal infection.
作者信息
Hopwood V, Warnock D W
出版信息
Eur J Clin Microbiol. 1986 Aug;5(4):379-88. doi: 10.1007/BF02075691.
PMID:3530748
Abstract
This review considers recent developments in the diagnosis of aspergillosis, candidosis and cryptococcosis and discusses the prospects for routine application of a number of novel methods. The introduction of lysis-centrifugation and radiometric methods for blood culture has improved the diagnosis of deep candidosis, but the value of these methods for the diagnosis of aspergillosis has not yet been determined. Recent developments in serological diagnosis have included the evaluation of newly discovered antigens of Candida albicans in an attempt to distinguish colonization from significant infection. Antigen detection, an established method for the diagnosis of cryptococcosis, has also been evaluated and appears promising for the diagnosis of aspergillosis and candidosis. Another promising approach has been the use of gas-liquid chromatography to detect fungal metabolites in serum and other host fluids.
摘要
本综述探讨了曲霉病、念珠菌病和隐球菌病诊断方面的最新进展，并讨论了一些新方法常规应用的前景。血液培养中裂解离心法和放射性测量法的引入改善了深部念珠菌病的诊断，但这些方法对曲霉病诊断的价值尚未确定。血清学诊断的最新进展包括对新发现的白色念珠菌抗原进行评估，以试图区分定植与严重感染。抗原检测作为隐球菌病的既定诊断方法也得到了评估，并且在曲霉病和念珠菌病的诊断中似乎很有前景。另一种有前景的方法是使用气液色谱法检测血清和其他宿主体液中的真菌代谢产物。
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