毒扁豆碱对乙酰胆碱酯酶的抑制作用：反应速率常数。第二部分。
Acetylcholinesterase inhibition by eserine: rate constants of reaction. Part II.
作者信息
Brufani M, Lippa S, Marta M, Oradei A, Pomponi M
出版信息
Ital J Biochem. 1985 Sep-Oct;34(5):328-40.
PMID:4077467
Abstract
The inhibition of eel acetylcholinesterase by physostigmine at 20 degrees and 25 degrees C have been investigated. In our evaluation the unimolecular reactivation rate constant, k3, the carbamylation rate constant, k2, and the binding constant, Ka, are the first simultaneously determined. The mechanism of this reaction is discussed.
摘要
已经研究了毒扁豆碱在20摄氏度和25摄氏度下对鳗鱼乙酰胆碱酯酶的抑制作用。在我们的评估中，首次同时测定了单分子复活速率常数k3、氨甲酰化速率常数k2和结合常数Ka。并对该反应的机制进行了讨论。
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