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马塞卢森卡塔纳诊所艾滋病毒感染者的高血压患病率及相关因素

Prevalence of hypertension and associated factors in people living with HIV at Senkatana Clinic Maseru.

作者信息

Selebalo Mosa S M, Bryden Benjamin J, Thompson David M, Sanders Jill E

机构信息

Department of Family Medicine, Family Medicine Specialty Training program, Lesotho Boston Health Alliance, Maseru, Lesotho; and General Practice, Ministry of Health, Maseru.

出版信息

Afr J Prim Health Care Fam Med. 2025 Jul 22;17(1):e1-e7. doi: 10.4102/phcfm.v17i1.4813.

Abstract

BACKGROUND

Cardiovascular diseases (CVDs), including hypertension (HTN), have emerged among people living with HIV (PLHIV) as the most important prevalent contributors of non-AIDS-related mortality. Moreover, HTN itself is a modifiable risk factor for other CVDs. Data are limited regarding the prevalence of HTN and associated factors among PLHIV in Lesotho.

AIM

To determine the prevalence of HTN and associated factors among PLHIV attending Senkatana ART Clinic.

SETTING

The study was carried out at Senkatana ART Clinic in urban Maseru, Lesotho.

METHODS

A cross-sectional study was conducted from February to July 2022. Data were analysed using SAS statistical software (v9.4) and Microsoft Excel. To determine HTN prevalence, blood pressure (BP) was measured, and a questionnaire was administered to participants who were randomly selected using the lottery method from the clinic's daily attendance list. Multiple logistic regression was used to assess factors associated with HTN in PLHIV while controlling for potentially confounding factors.

RESULTS

The prevalence of HTN was 57% (exact 95% CI: 51.2%, 62.7%). Of those with HTN, 33.3% were newly diagnosed during this study (exact 95% CI: 26.3%, 40.9%), while 69% of those previously diagnosed with HTN had uncontrolled HTN at enrollment (exact 95% CI: 60.0%, 77.6%). Age older than 50 years (p  0.0001) and a body mass index (BMI) of 25.0 kg/m2 or higher (p  0.0002) were independently associated with HTN.

CONCLUSION

Hypertension was highly prevalent and poorly controlled. Factors associated with HTN in PLHIV were older age and higher BMI. The study's findings support models of comprehensive healthcare delivery.

摘要

背景

包括高血压(HTN)在内的心血管疾病(CVDs)在人类免疫缺陷病毒(HIV)感染者(PLHIV)中已成为非艾滋病相关死亡率的最重要普遍因素。此外,高血压本身是其他心血管疾病的一个可改变的风险因素。关于莱索托PLHIV中高血压的患病率及相关因素的数据有限。

目的

确定在森卡塔纳抗逆转录病毒治疗诊所就诊的PLHIV中高血压的患病率及相关因素。

地点

该研究在莱索托马塞卢市区的森卡塔纳抗逆转录病毒治疗诊所进行。

方法

于2022年2月至7月进行了一项横断面研究。使用SAS统计软件(v9.4)和Microsoft Excel对数据进行分析。为确定高血压患病率,测量了血压,并向从诊所每日出勤名单中通过抽签法随机选择的参与者发放了问卷。在控制潜在混杂因素的同时,使用多因素逻辑回归评估PLHIV中与高血压相关的因素。

结果

高血压患病率为57%(精确95%CI:51.2%,62.7%)。在患有高血压的人群中,33.3%是在本研究期间新诊断出的(精确95%CI:26.3%,40.9%),而在之前被诊断患有高血压的人群中,69%在入组时高血压未得到控制(精确95%CI:60.0%,77.6%)。年龄大于50岁(p < 0.0001)和体重指数(BMI)为25.0kg/m2或更高(p < 0.0002)与高血压独立相关。

结论

高血压患病率很高且控制不佳。PLHIV中与高血压相关的因素是年龄较大和BMI较高。该研究结果支持全面医疗服务提供模式。

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