Ecole Doctorale des Sciences de la Santé (EDSS), University of Abomey Calavi, Abomey Calavi, Benin.
Laboratoire ses Maladies Chroniques et Neurologiques (LEMACEN), Abomey Calavi, Benin.
Sci Rep. 2024 Jul 24;14(1):17035. doi: 10.1038/s41598-024-64212-3.
Antiretroviral therapy (ART) has extended the lifespan of people living with HIV/AIDS (PLHIV), exposing them to a higher risk of cardiovascular diseases (CVD). Hypertension (HTN), the primary contributor to CVD burden, is increasingly concerning for PLHIV. This study aimed to assess the prevalence and associated factors of hypertension in PLHIV on ART at the National Teaching Hospital Hubert Koutoukou Maga (HKM) of Benin using a prospective cross-sectional study conducted between October and December 2021. Patients who had a systolic blood pressure ≥ 140 mmHg or/and diastolic blood pressure ≥ 90 mmHg or/and current use of antihypertensive medication from medical records were considered to have HTN. A total of 352 patients, including 260 women with a sex ratio of 0.3 were included. The mean age was 42.9 ± 11.9 years. Most patients were educated and did not use tobacco. 42.0% were current alcohol drinkers. The duration of ART treatment ranged from 0 to 22 years, with a median duration of 5.0 years. 14.2% were hypertensives with 3.1% newly diagnosed and 11.1% known with hypertension. Age above 40 years, living with a partner, alcohol consumption and body mass index greater than 25 were significantly associated with HTN. HTN in PLHIV is associated with numerous factors. Reducing the burden of the disease in target people in Benin requires a wide range of actions that need to be implemented.
抗逆转录病毒疗法（ART）延长了艾滋病毒/艾滋病（PLHIV）患者的寿命，使他们面临更高的心血管疾病（CVD）风险。高血压（HTN）是 CVD 负担的主要原因，越来越引起 PLHIV 的关注。本研究旨在使用 2021 年 10 月至 12 月期间进行的前瞻性横断面研究，评估贝宁国家教学医院 Hubert Koutoukou Maga（HKM）接受 ART 的 PLHIV 中高血压的患病率及其相关因素。根据病历，收缩压≥140mmHg 和/或舒张压≥90mmHg 和/或正在使用降压药物的患者被认为患有 HTN。共纳入 352 例患者，其中 260 例为女性，性别比为 0.3。平均年龄为 42.9±11.9 岁。大多数患者受过教育，不吸烟。42.0%为当前饮酒者。ART 治疗时间从 0 到 22 年不等，中位数为 5.0 年。14.2%为高血压患者，其中 3.1%为新诊断的，11.1%为已知高血压患者。年龄超过 40 岁、与伴侣同居、饮酒和 BMI 大于 25 与 HTN 显著相关。PLHIV 中的 HTN 与许多因素有关。要减轻贝宁目标人群中该疾病的负担，需要采取广泛的行动，这些行动需要得到实施。
