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对2025年来自沙特阿拉伯、意大利的四名旅行者中引起侵袭性脑膜炎球菌病的W血清群进行基因组分析。

Genomic analysis of serogroup W causing invasive meningococcal disease in four travellers from Saudi Arabia, Italy, 2025.

作者信息

Neri Arianna, Taviani Elsa, Ferraro Federica, Maraglino Francesco, Marra Manuela, Daprai Laura, Vocale Caterina, Vian Elisa, Palamara Anna Teresa, Stefanelli Paola

机构信息

Department of Infectious Diseases, Istituto Superiore di Sanità (ISS), Rome, Italy.

Italian Ministry of Health, Rome, Italy.

出版信息

Euro Surveill. 2025 Aug;30(31). doi: 10.2807/1560-7917.ES.2025.30.31.2500483.

Abstract

Genomic analysis was performed on isolates from four cases of invasive meningococcal disease (IMD) identified in Italy after travel to Saudi Arabia in 2025. The cases were not epidemiologically related. The isolates from the cases were whole genome sequenced and belonged to serogroup W, sequence type (ST)-11, clonal complex (CC)11 and were susceptible to ceftriaxone, ciprofloxacin, penicillin G and rifampicin. Phylogenetic analysis grouped the four genomes with the Hajj strain sublineage.

摘要

对2025年前往沙特阿拉伯后在意大利确诊的4例侵袭性脑膜炎球菌病(IMD)病例的分离株进行了基因组分析。这些病例在流行病学上无关联。对这些病例的分离株进行了全基因组测序,它们属于W血清群、序列型(ST)-11、克隆复合体(CC)11,并且对头孢曲松、环丙沙星、青霉素G和利福平敏感。系统发育分析将这四个基因组与朝觐菌株亚系归为一组。

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