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2024年1月至2025年6月期间,英格兰与前往沙特阿拉伯朝圣相关的W群侵袭性脑膜炎球菌病增加。

Increase in serogroup W invasive meningococcal disease in England associated with pilgrimage to Saudi Arabia, January 2024 to June 2025.

作者信息

Campbell Helen, Lucidarme Jay, Clark Stephen A, Heymer Emma J, Ribeiro Sonia, Bai Xilian, Ahmad Shazaad, Ramsay Mary E, Borrow Ray, Ladhani Shamez N

机构信息

Immunisation and Vaccine Preventable Diseases Division, UK Health Security Agency, Colindale, London, United Kingdom.

Meningococcal Reference Unit, UK Health Security Agency, Manchester Royal Infirmary, Manchester, United Kingdom.

出版信息

Euro Surveill. 2025 Aug;30(31). doi: 10.2807/1560-7917.ES.2025.30.31.2500509.

Abstract

England is experiencing an increase in serogroup W invasive meningococcal disease (IMD) caused by 'strain A' of the meningococcal sequence type 11 clonal complex (MenW:cc11) Hajj strain sublineage. Travel-associated and non-travel-associated meningococci from four strain A substrains (A1-A4) accounted for 32 of 59 MenW IMD cases between January 2024 and June 2025, 14 in people returning from Saudi Arabia or household contacts; eight of 14 linked to Umrah pilgrimage. Communications about MenACWY vaccination for pilgrims year-round should be reinforced.

摘要

英格兰正经历由脑膜炎球菌序列型11克隆复合体(MenW:cc11)朝觐菌株亚谱系的“A菌株”引起的W血清群侵袭性脑膜炎球菌病(IMD)病例增加。2024年1月至2025年6月期间,来自四个A菌株亚菌株(A1 - A4)的与旅行相关和与旅行无关的脑膜炎球菌占59例MenW IMD病例中的32例,其中14例为从沙特阿拉伯返回的人员或其家庭接触者;14例中有8例与副朝朝圣有关。应加强针对朝圣者全年的MenACWY疫苗接种宣传。

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