Liu Yu-Xiao, Han Yan-Hua, Jiang Yue, Zhang Jiao, Zhang Yue-Hui
First Clinical Medical College, Heilongjiang University of Chinese Medicine, Harbin, China.
Gynecology I Department, First Affiliated Hospital Heilongjiang University of Chinese Medicine, Harbin, China.
Front Med (Lausanne). 2025 Jul 24;12:1531506. doi: 10.3389/fmed.2025.1531506. eCollection 2025.
Traditional Chinese medicine (TCM) has seen a surge in interest in acupuncture as a treatment for polycystic ovary syndrome (PCOS), a condition marked by hyperandrogenism, irregular ovulation, and polycystic ovaries. Acupuncture has been shown to dramatically lower androgen levels in PCOS patients; this effect may be achieved by reducing the secretion of neurotransmitters in the hypothalamic-pituitary-gonadal (HPG) axis and interfering with the hypothalamic-pituitary-adrenal (HPA) axis and its cortisol release. Furthermore, by enhancing glucose metabolism, decreasing inflammation in adipose tissue, and enhancing intercellular communication pathways, acupuncture may indirectly address hyperandrogenemia. Although acupuncture has the potential to treat PCOS, further research is necessary to fully understand its mechanism. It is advised that more clinical research integrating molecular biology and biochemical methods be conducted in the future to determine the precise mechanism of acupuncture's effects on PCOS and to offer new suggestions for managing the condition's symptoms.
传统中医(TCM)中,针灸作为治疗多囊卵巢综合征(PCOS)的一种方法,其关注度激增。多囊卵巢综合征的特征为雄激素过多、排卵不规律和多囊卵巢。研究表明,针灸可显著降低PCOS患者的雄激素水平;这种效果可能是通过减少下丘脑-垂体-性腺(HPG)轴中神经递质的分泌以及干扰下丘脑-垂体-肾上腺(HPA)轴及其皮质醇释放来实现的。此外,通过增强葡萄糖代谢、减轻脂肪组织炎症以及增强细胞间通讯途径,针灸可能间接解决雄激素过多症。尽管针灸有治疗PCOS的潜力,但仍需进一步研究以全面了解其机制。建议未来开展更多整合分子生物学和生化方法的临床研究,以确定针灸对PCOS作用的精确机制,并为该病症症状的管理提供新建议。