乌干达糖尿病和高血压患者中抑郁症及自杀意念的患病率及其相关因素

Prevalence and factors associated with depression and suicidal ideation among people with diabetes mellitus and hypertension in Uganda.

作者信息

Nkola Rahel, Kaggwa Mark Mohan, Muwanguzi Moses, Kule Moses, Rukundo Godfrey Zari, Ashaba Scholastic

机构信息

Department of Psychiatry, Faculty of Medicine, Mbarara University of Science and Technology, Uganda.

African Centre for Suicide Prevention and Research, Mbarara, Uganda.

出版信息

Afr Health Sci. 2024 Sep;24(3):361-374. doi: 10.4314/ahs.v24i3.40.

DOI:10.4314/ahs.v24i3.40

PMID:40777929

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12327146/

Abstract

BACKGROUND

Depression and suicide ideation are more common among patients with chronic physical illness including diabetes mellitus (DM) and hypertension (HTN). Depression is often undetected, underdiagnosed, and undertreated during routine care and may complicate into suicidal ideation in this population. This study aimed to determine the prevalence of depression and suicidal ideation, and associated factors among people living with DM and/or HTN in Uganda.

METHODS

We enrolled 512 participants and assessed depression using PHQ-9, and suicidal ideation using item 9 of PHQ-9. We run logistic regression models to determine the factors associated with depression and suicidal ideation among those with DM only, HTN only or both.

RESULTS

The overall prevalence of depression and suicidal ideation was 22.07% and 10%, respectively. Among participants with both DM&HTN the prevalence of depression was 26.3% while 30.4% had comorbid suicidal ideation. Fear of complications (AOR = 7.21; 95% CI =2.68-19.39; p = 0.01) was significantly associated with depression. Adherence on antidiabetic medications (AOR = 0.10; 95% CI = 0.02-0.72; p = 0.02) was protective against depression.

CONCLUSION

The prevalence of depression and suicidal ideation among patients with DM and/or HTN in Uganda is high.

摘要

背景

抑郁症和自杀意念在包括糖尿病（DM）和高血压（HTN）在内的慢性躯体疾病患者中更为常见。在常规护理中，抑郁症常常未被发现、诊断不足且治疗不充分，在这一人群中可能会发展为自杀意念。本研究旨在确定乌干达糖尿病和/或高血压患者中抑郁症和自杀意念的患病率及其相关因素。

方法

我们招募了512名参与者，使用PHQ-9评估抑郁症，使用PHQ-9的第9项评估自杀意念。我们进行逻辑回归模型分析，以确定仅患有糖尿病、仅患有高血压或两者皆有的患者中与抑郁症和自杀意念相关的因素。

结果

抑郁症和自杀意念的总体患病率分别为22.07%和10%。在患有糖尿病和高血压的参与者中，抑郁症的患病率为26.3%，而有合并自杀意念的患病率为30.4%。对并发症的恐惧（比值比[AOR]=7.21；95%置信区间[CI]=2.68-19.39；p=0.01）与抑郁症显著相关。坚持服用抗糖尿病药物（AOR=0.10；95%CI=0.02-0.72；p=0.02）对抑郁症有预防作用。