嗜铬细胞瘤诱发的心肌病，手术切除后需要机械循环支持并实现心脏恢复。

Pheochromocytoma-Induced Cardiomyopathy Requiring Mechanical Circulatory Support With Cardiac Recovery Following Surgical Resection.

作者信息

Garrison Phillip Grant, East Lauren, Wanna Charles, Paudel Bishow, Tallaj Jose, McElwee Samuel, Lindeman Brenessa, Clarkson Stephen

机构信息

Department of Internal Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Alabama, USA.

出版信息

JACC Case Rep. 2025 Aug 6;30(22):104564. doi: 10.1016/j.jaccas.2025.104564.

DOI:10.1016/j.jaccas.2025.104564

PMID:40780756

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12426538/

Abstract

BACKGROUND

Although exceedingly rare, pheochromocytomas can present with heart failure and cardiogenic shock, leading to complex management considerations.

CASE SUMMARY

A 49-year-old woman presented with chest pain and palpitations, and ultimately developed cardiogenic shock secondary to a pheochromocytoma. She required Impella 5.5 preceded by Impella CP (Abiomed) and venoarterial extracorporeal membrane oxygenation support as a bridge to surgical resection. After adrenalectomy, she was weaned from mechanical circulatory support, with recovery of left ventricular function.

DISCUSSION

Pheochromocytomas are rare catecholamine-secreting tumors. Patients typically present with episodic headache, sweating, and tachycardia; however, pheochromocytomas can be associated with cardiomyopathy secondary to the catecholamine excess. Mechanical circulatory support can serve as a safe and effective approach to stabilize patients while awaiting tumor resection.

TAKE-HOME MESSAGES: Mechanical circulatory support is a valuable adjunct in managing refractory heart failure by providing temporary hemodynamic stabilization while awaiting tumor resection. Ejection fraction can recover after removal of catecholamine-induced myocardial injury.

摘要