Inoue Y
Nihon Sanka Fujinka Gakkai Zasshi. 1985 Oct;37(10):1997-2004.
The structural characteristics and site of origin of the resurfacing uterine lining, as well as the influence of ovarian hormonal stimuli on the reparative processes of experimentally injured endometrium in women, were studied by means of cytology, light microscopy and electron microscopy. In exfoliative cytology, the cells which seemed to be derived from the surface layer showed nuclear enlargement, anisonucleosis, hyperchromasia and prominent nucleoli. The repair of the uterine surface was completed within 4 days following the first 24 hours, after mechanically inducing trauma. After complete reepithelialization, regeneration of the secretory endometrium appeared even more markedly delayed than that of proliferative endometrium. The mechanism of recovery of the denuded surface was due to a progressive epithelial outgrowth from the mouths of basal glands. The resurfacing cells were epithelial in nature. Stromal cells which appeared to project between gland stumps and take part in the reepithelialization by a process simultating metaplasia were not recognized. It was suggested that the newly formed surface lining was derived from the stumps of residual basal glands.
通过细胞学、光学显微镜和电子显微镜研究了子宫内膜再生的结构特征、起源部位，以及卵巢激素刺激对女性实验性损伤子宫内膜修复过程的影响。在脱落细胞学检查中，似乎来源于表层的细胞表现为细胞核增大、核大小不均、染色质增多和核仁突出。在机械性造成创伤后的最初24小时内，子宫表面的修复在4天内完成。完全上皮化后，分泌期子宫内膜的再生比增殖期子宫内膜的再生明显延迟。裸露表面的恢复机制是由于基底腺开口处上皮细胞逐渐生长。再生的细胞本质上是上皮细胞。未发现似乎在腺残端之间突出并通过类似化生的过程参与上皮化的基质细胞。提示新形成的表面内膜来源于残留基底腺的残端。
