Ferenczy A
Am J Obstet Gynecol. 1977 Jul 1;128(5):536-45. doi: 10.1016/0002-9378(77)90038-2.
The kinetic and fine structural characteristics and site of origin of the resurfacing uterine lining, as well as the influence of ovarian hormonal stimuli on the reparative processes of experimentally injured endometrium in the rabbit, were studied by means of in vivo historadioautography and electron microscopy. The first-generation, resurfacing spindle-shaped cells lacked mitosis and expanded by ameboid migration. This was followed by a rapid increase in nuclear deoxyribonucleic acid synthesis, which presumably provided for accelerated mitosis-mediated surface epithelial proliferation and maturation. By Day 3 after injury, endometrial regeneration was completed with a return of labeling index to base-line levels. The newly formed surface lining was derived exclusively from the persistent surface epithelium bordering the denuded regions. The isotope uptake and morphologic alterations of the regenerating endometrium in castrated rabbits which were similar to those of intact rabbits suggest that endometrial repair is not mediated by the hormones of the reproductive system.
通过体内组织放射自显影术和电子显微镜，研究了兔子宫内膜再生的动力学、精细结构特征、起源部位，以及卵巢激素刺激对实验性损伤子宫内膜修复过程的影响。第一代再生的梭形细胞无有丝分裂，通过阿米巴样迁移而扩展。随后，核脱氧核糖核酸合成迅速增加，这可能为有丝分裂介导的表面上皮细胞增殖和成熟加速提供了条件。损伤后第3天，子宫内膜再生完成，标记指数恢复到基线水平。新形成的表面内膜完全源自与剥脱区域相邻的残留表面上皮。去势兔再生子宫内膜的同位素摄取和形态学改变与完整兔相似，这表明子宫内膜修复不受生殖系统激素的介导。
