Hanek Kamil, Żak Patrycja
Department of Organometallic Chemistry, Faculty of Chemistry, Adam Mickiewicz University in Poznań, Uniwersytetu Poznańskiego 8, 61-614, Poznań, Poland.
Sci Rep. 2025 Aug 11;15(1):29286. doi: 10.1038/s41598-025-14360-x.
Commercially available and inexpensive potassium carbonate (KCO) has been applied to the hydrothiolation of mercaptopropylisobutyl POSS (SQ-SH) with α,β-unsaturated carbonyl compounds of different types. This innovative approach has been proved to be effective for a wide range of substrates, leading to novel classes of functionalized SQ-based materials in yields exceeding 90% under ambient temperature, air and transition metal-free conditions. Additionally, the proposed synthetic strategy has been used for the modification of chalcones, the compounds with significant medicinal and synthetic potential. As a result, twelve new mercapto-modified nanomaterials containing carbonyl groups were obtained and comprehensively characterized by spectroscopic methods and mass analysis. The selected product of great practical application was studied in terms of its thermal properties.
市售且价格低廉的碳酸钾（KCO）已被应用于巯基丙基异丁基倍半硅氧烷（SQ-SH）与不同类型的α,β-不饱和羰基化合物的氢硫基化反应。这种创新方法已被证明对多种底物有效，在常温、空气和无过渡金属条件下，能以超过90%的产率生成新型的功能化SQ基材料。此外，所提出的合成策略已用于修饰查耳酮，这类化合物具有重要的药用和合成潜力。结果，获得了十二种新的含羰基的巯基修饰纳米材料，并通过光谱方法和质谱分析进行了全面表征。对具有重大实际应用价值的所选产物进行了热性能研究。
