Winklbauer R, Hausen P
J Embryol Exp Morphol. 1985 Aug;88:193-207.
The periodic pattern of the supraorbital lateral line organs forms in the epidermis of Xenopus by the subdivision of a streak-like primordium into a linear series of small cell groups. In normal development, each such organ initially contains about 8 cells (Winklbauer & Hausen, 1983a,b). To see whether this initial organ size depends on the size of the streak-like primordium at the time of organ segregation, primordium size was reduced experimentally before the onset of pattern formation. In such small primordia, the size of the primary organs formed is not adjusted so as to allow the formation of a normal number of organs. Instead, the initial organ size is kept approximately normal, and the number of organs is correspondingly reduced, i.e. the pattern forming mechanism is not capable of 'size regulation'.
眶上侧线器官的周期性模式在非洲爪蟾的表皮中形成，是通过将条纹状原基细分为一系列小细胞群的线性排列。在正常发育过程中，每个这样的器官最初约含8个细胞（温克尔鲍尔和豪森，1983a，b）。为了观察这种初始器官大小是否取决于器官分离时条纹状原基的大小，在模式形成开始前通过实验减小了原基大小。在如此小的原基中，所形成的初级器官的大小并未进行调整以允许形成正常数量的器官。相反，初始器官大小大致保持正常，而器官数量相应减少，即模式形成机制不具备“大小调节”能力。
