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[二尖瓣和二尖瓣-主动脉瓣疾病人工瓣膜修复术后三尖瓣关闭不全矫正与未矫正的结果。附159例报告]

[Outcome of corrected and uncorrected tricuspid insufficiency after repair with prostheses in mitral and mitro-aortic valve diseases. Apropos of 159 cases].

作者信息

Ben-Ismail M, Richard C, Kamoun M, Enriquez-Sarano L, Cabane J

出版信息

Arch Mal Coeur Vaiss. 1977 May;70(5):461-8.

PMID:407858
Abstract

This is a study of 159 patients with tricuspid incompetence (TI) associated with a mitral or mitro-aortic valve defect. The mean age of the patients at operation was 25.5 years. The TI was left untreated in 84, corrected by semi-circular annuloplasty in 39, and corrected by a prothesis in 28, by a Carpentier ring in 6, and by Kay's plasty in 2. The 33 early deaths (21%) are regrettable. The long-term outlook was studied with a mean follow-up period of 26 months. The overall mortality rises, if these are included, to 42 (26%). By comparing the preoperative findings in those with good and poor results, we have been able to identify a certain number of risk factors: a preoperative course of greater than or equal to 6 years, a number of attacks of cardiac failure greater than or equal to 3, a cardiothoracic ratio greater than or equal to 0.70, a mean right atrial pressure greater than 12, a mean pulmonary arterial pressure of greater than or equal to 50. Severe TI is also a poor prognostic factor. If the three groups of patients are compared, bearing in mind the fact that their preoperative state was very similar, and that the TI was either left untreated or repaired by annuloplasty or prosthesis, it appears that such a correction improves neither the surgical mortality nor the long-term prognosis. It therefore seems to us that a functional TI can be treated expectantly since its resolution depends more on the unified treatment of the whole underlying disorder and on the state of the myocardium than on any localised correction of the TI.

摘要

这是一项针对159例伴有二尖瓣或二尖瓣 - 主动脉瓣缺损的三尖瓣关闭不全(TI)患者的研究。患者手术时的平均年龄为25.5岁。84例患者的TI未治疗,39例通过半圆形瓣环成形术矫正,28例通过人工瓣膜矫正,6例通过Carpentier环矫正,2例通过Kay成形术矫正。33例早期死亡(21%)令人遗憾。研究了长期预后,平均随访期为26个月。如果将这些早期死亡病例包括在内,总死亡率升至42例(26%)。通过比较预后良好和不良患者的术前检查结果,我们能够确定一些危险因素:术前病程大于或等于6年、心力衰竭发作次数大于或等于3次、心胸比率大于或等于0.70、平均右心房压力大于12、平均肺动脉压力大于或等于50。严重TI也是一个不良预后因素。如果比较三组患者,考虑到他们术前状态非常相似,且TI要么未治疗,要么通过瓣环成形术或人工瓣膜修复,那么似乎这种矫正既不能改善手术死亡率,也不能改善长期预后。因此,在我们看来,功能性TI可以进行观察性治疗,因为其转归更多地取决于整个潜在疾病的综合治疗以及心肌状态,而非TI的任何局部矫正。

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