面部和颈部除皱术后急性局限性脓疱性银屑病：一个抵抗力较弱部位的病例

Fort Liliana, Seminario-Vidal Lucia, Pepper Amber N, Billington Alicia

From the Shorecrest Preparatory School, St. Petersburg, FL.

Weinkle Dermatology, Bradenton, FL.

Plast Reconstr Surg Glob Open. 2025 Aug 8;13(8):e7052. doi: 10.1097/GOX.0000000000007052. eCollection 2025 Aug.

We report a case of a 52-year-old woman who developed acute localized exanthematous pustulosis, a rare drug reaction, after cefazolin administration for a face and neck surgery. The rash was confined to the surgical areas, suggesting a locus minoris resistentiae, a phenomenon where a site of previous injury becomes more vulnerable to a subsequent insult. The rash resolved with corticosteroids. We review the clinical features, causes, and management of acute localized exanthematous pustulosis.

我们报告了一例52岁女性病例，该患者在接受面部和颈部手术后因使用头孢唑林而发生急性局限性脓疱性皮疹，这是一种罕见的药物反应。皮疹局限于手术区域，提示存在抵抗力较弱部位，即先前受伤部位更容易受到后续损伤的现象。皮疹通过使用皮质类固醇得以消退。我们对急性局限性脓疱性皮疹的临床特征、病因及治疗进行了综述。