Akbayrak Atiye, Yazar Cemre, Alev Deresoy Faik, Sencan Mehtap, Yildiz Seckin Havva, Kutlu Omer
Department of Dermatology and Venereology, School of Medicine, Gaziosmanpasa University, Tokat, Turkey.
Department of Pathology, School of Medicine, Gaziosmanpasa University, Tokat, Turkey.
Int J Dermatol. 2022 Jun;61(6):707-709. doi: 10.1111/ijd.16044. Epub 2022 Jan 7.
Acute localized exanthematous pustulosis (ALEP), a localized variant of acute generalized exanthematous pustulosis, is characterized by pin-sized, non-follicular, sterile pustules that typically appear on the face, neck, and chest.
The purpose of this report is to describe a case of ALEP in an 11-year-old girl because of cefixime and the etiological factors and clinical presentation of ALEP in pediatric group.
We described a case of ALEP in an 11-year-old girl because of cefixime; a systematic review of the literature was performed to identify the etiological factors and clinical presentation of ALEP in children.
We identified eight pediatric cases with ALEP. The causative agent was an herbal product in six cases, and pustular eruption was located on the face. In two cases, responsible agents were drugs (lamotrigine and amoxicillin-clavulanic acid). The eruptions were localized on the penis and extremities, respectively.
ALEP is very rare in the pediatric age group, and topical/systemic drugs or herbal products may be involved in the etiology.
急性局限性脓疱性皮疹（ALEP）是急性泛发性脓疱性皮疹的一种局限性变体，其特征为针尖大小、非毛囊性的无菌脓疱，通常出现在面部、颈部和胸部。
本报告旨在描述一例11岁女孩因头孢克肟引发的ALEP病例，以及儿科人群中ALEP的病因和临床表现。
我们描述了一例11岁女孩因头孢克肟引发的ALEP病例；对文献进行了系统回顾，以确定儿童ALEP的病因和临床表现。
我们确定了8例儿童ALEP病例。6例的致病原为一种草药产品，脓疱疹位于面部。2例的致病原为药物（拉莫三嗪和阿莫西林-克拉维酸），皮疹分别位于阴茎和四肢。
ALEP在儿科年龄组中非常罕见，局部/全身用药或草药产品可能与病因有关。
