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酷似脊髓肿瘤的脊髓粘连性蛛网膜炎:一例报告

Spinal Adhesive Arachnoiditis Mimicking a Spinal Tumor: A Case Report.

作者信息

Bamrah Jotdeep S, Keshri Vikrant, Joshi Deepak, Bamania Sarav

机构信息

Neurosurgery, Smt. B. K. Shah (SBKS) Medical Institute and Research Centre, Sumandeep Vidyapeeth (Deemed University), Vadodara, IND.

出版信息

Cureus. 2025 Jul 9;17(7):e87638. doi: 10.7759/cureus.87638. eCollection 2025 Jul.

Abstract

Spinal adhesive arachnoiditis (SAA) is a rare condition of the meningeal layers of the spinal cord and nerve roots, which can lead to disability. Our patient was a 44-year-old female with a history of cervical spine surgery, followed by external lumbar drain insertion for cerebrospinal fluid (CSF) diversion three years ago. She presented with gradually worsening back pain and bilateral leg weakness. Initial evaluation and MRI of the lumbosacral spine suggested the presence of a spinal tumor. She underwent lumbar spine surgery. But no tumor was identified intra-op; instead, dense arachnoid adhesions encasing the nerve roots were identified, for which partial adhesiolysis was done. Surprisingly, the retained proximal catheter of the lumbar drain was found embedded within adhesions encasing the nerve roots. How it was left in place and missed during the previous drain removal remains unknown and is not documented in the prior treatment records. Though MRI is the most sensitive and specific diagnostic imaging, SAA can mimic an intradural tumor. Despite current knowledge of the nature of adhesive arachnoiditis, as well as advances in treatment and intensive rehabilitation, there are still no established guidelines for prophylaxis, and neurological improvement remains rare. This case report highlights the possible pathophysiology, causes of SAA, and treatment options available for this rare condition.

摘要

脊髓粘连性蛛网膜炎(SAA)是一种累及脊髓和神经根脑膜层的罕见病症,可导致残疾。我们的患者是一名44岁女性,有颈椎手术史,三年前因脑脊液(CSF)引流插入了外置腰大池引流管。她出现了逐渐加重的背痛和双侧腿部无力。腰骶部脊柱的初步评估和MRI提示存在脊髓肿瘤。她接受了腰椎手术。但术中未发现肿瘤;相反,发现神经根被致密的蛛网膜粘连包裹,为此进行了部分粘连松解术。令人惊讶的是,发现腰大池引流管残留的近端导管嵌入了包裹神经根的粘连中。它是如何留在原处且在之前拔除引流管时未被发现的仍不清楚,且先前的治疗记录中未记载。尽管MRI是最敏感和特异的诊断成像,但SAA可模仿硬脊膜内肿瘤。尽管目前对粘连性蛛网膜炎的性质有所了解,且在治疗和强化康复方面取得了进展,但仍没有既定的预防指南,神经功能改善仍然很少见。本病例报告强调了SAA可能存在的病理生理学、病因以及针对这种罕见病症的可用治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08a5/12335326/f655b854e867/cureus-0017-00000087638-i01.jpg

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本文引用的文献

1
Spinal adhesive arachnoiditis: three case reports and review of literature.
Acta Neurol Belg. 2021 Feb;121(1):47-53. doi: 10.1007/s13760-020-01431-1. Epub 2020 Aug 24.
2
The presence of arachnoiditis affects the characteristics of CSF flow in the spinal subarachnoid space: a modelling study.
J Biomech. 2012 Apr 30;45(7):1186-91. doi: 10.1016/j.jbiomech.2012.01.050. Epub 2012 Mar 3.
3
Novel surgical management of spinal adhesive arachnoiditis by arachnoid microdissection and ventriculo-subarachnoid shunting.
J Clin Neurosci. 2011 Dec;18(12):1702-4. doi: 10.1016/j.jocn.2011.03.014. Epub 2011 Oct 22.
5
6
Antiseptic solutions for central neuraxial blockade: which concentration of chlorhexidine in alcohol should we use?
Br J Anaesth. 2009 Sep;103(3):456; author reply 456-7. doi: 10.1093/bja/aep214.
8
Obstetric epidurals and chronic adhesive arachnoiditis.
Br J Anaesth. 2004 Jan;92(1):109-20. doi: 10.1093/bja/aeh009.
9
Surgical management of syringomyelia associated with spinal adhesive arachnoiditis.
J Clin Neurosci. 2001 Jan;8(1):40-2. doi: 10.1054/jocn.2000.0731.
10
Tuberculous radiculomyelitis complicating tuberculous meningitis: case report and review.
Clin Infect Dis. 2000 Jun;30(6):915-21. doi: 10.1086/313821. Epub 2000 Jun 14.

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