Chowdhury Anayah, Bhasin Garv, Ganti Latha
Research, Canterbury School, Fort Myers, USA.
Biology, Brown University, Providence, USA.
Cureus. 2025 Jul 7;17(7):e87484. doi: 10.7759/cureus.87484. eCollection 2025 Jul.
Alzheimer's disease presents a complex global health issue. It is characterized by a decline in cognitive function, starting with memory impairment, and extending to impact reasoning, language abilities, and spatial awareness. Despite decades of research, Alzheimer's disease remains a global challenge lacking long-term treatments. Institutions like the Karolinska Institutet, Columbia University, the University of California San Francisco (UCSF), and the University of Pittsburgh contribute significantly to Alzheimer's research, with a growth in publications in 2022 post-COVID-19. While current treatments offer symptomatic relief, there's a need for disease-modifying therapies targeting its mechanisms. This analysis aims to provide a comprehensive overview of the available research and medical literature on Alzheimer's disease by employing bibliometric methods to identify publication trends, leading research institutions, and the evolving focus from symptomatic treatments to disease-modifying therapies. This paper seeks to analyze the research papers on Alzheimer's disease and catalog the metadata associated with each paper.
阿尔茨海默病是一个复杂的全球健康问题。其特征是认知功能下降，始于记忆障碍，并扩展到影响推理、语言能力和空间意识。尽管经过了数十年的研究，但阿尔茨海默病仍然是一个缺乏长期治疗方法的全球性挑战。卡罗林斯卡学院、哥伦比亚大学、加利福尼亚大学旧金山分校（UCSF）和匹兹堡大学等机构对阿尔茨海默病研究做出了重大贡献，2022年新冠疫情后相关出版物有所增加。虽然目前的治疗方法能缓解症状，但仍需要针对其发病机制的疾病修饰疗法。本分析旨在通过文献计量方法全面概述有关阿尔茨海默病的现有研究和医学文献，以确定出版趋势、主要研究机构，以及从对症治疗到疾病修饰疗法的研究重点演变。本文旨在分析关于阿尔茨海默病的研究论文，并编目与每篇论文相关的元数据。
