肾移植患者中……的血清流行病学。（原文中“of”后面内容缺失）

Seroepidemiology of in kidney transplant patients.

作者信息

Latifi Marzieh, Rahban Habib, Pourhosein Elahe, Hajialireza Tehrani Tannaz, Mahjoobi Parisa, Dehghani Sanaz

机构信息

Department of Public Health, School of Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Creighton University School of Medicine, St. Joseph Hospital and Medical Center, Department of Cardiovascular Disease, Phoenix, Arizona.

出版信息

Caspian J Intern Med. 2025 Jun 23;16(3):507-512. doi: 10.22088/cjim.16.3.507. eCollection 2025 Summer.

DOI:10.22088/cjim.16.3.507

PMID:40786582

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12329353/

Abstract

BACKGROUND

Opportunistic infection after transplantation is a serious problem, with and cytomegalovirus being the most concerning infections. The objective of this research was to examine the seroepidemiology of the virus among kidney transplant recipients at Sina Hospital in Tehran from 2017 to 2021.

METHODS

A total of 342 kidney transplant patients participated in this cross-sectional study using the census method after obtaining consent. Data were collected by reviewing medical records and the transplant database, including demographic characteristics and infectious tests related to kidney transplantation. The collected information was entered into SPSS18 software.

RESULTS

The age of the subjects ranged from 10 to 73 years, with 125 patients having kidney failure due to ERDS. The rate of exposure to T. gondii in kidney transplant patients was 54.2%. 125 patients experiencing kidney failure due to ERDS. In kidney transplant patients, the exposure rate to was 54.2%. There is a positive correlation between and age (r= 0.12, P = 0.02). There is a positive correlation between and the time elapsed since kidney transplantation (r = 0.11, P = 0.03) and (r = 0.13, p < 0.01). Gender was found not to predict (β = 0.787, p < 0.21 (β = 4.752, p < 0.071), (β = 1.154, p < 0.256) based on regression tests.

CONCLUSION

Physicians should be aware of preventive measures and should consider early diagnosis in cases of compatible symptoms. Screening for anti-Toxoplasma IgM antibodies in potential donors is recommended.

摘要

背景

移植后的机会性感染是一个严重问题，其中[具体病毒名称1]和巨细胞病毒是最令人担忧的感染。本研究的目的是调查2017年至2021年德黑兰锡纳医院肾移植受者中[具体病毒名称1]病毒的血清流行病学。

方法

在获得同意后，采用普查方法，共有342名肾移植患者参与了这项横断面研究。通过查阅病历和移植数据库收集数据，包括人口统计学特征和与肾移植相关的感染检测。将收集到的信息录入SPSS18软件。

结果

受试者年龄在10至73岁之间，125名患者因ERDS导致肾衰竭。肾移植患者中[具体病毒名称1]的暴露率为54.2%。125名患者因ERDS导致肾衰竭。在肾移植患者中，[具体病毒名称1]的暴露率为54.2%。[具体病毒名称1]与年龄呈正相关（r = 0.12，P = 0.02）。[具体病毒名称1]与肾移植后经过的时间呈正相关（r = 0.11，P = 0.03）以及[相关因素2]呈正相关（r = 0.13，p < 0.01）。根据回归测试，发现性别不能预测[具体病毒名称1]（β = 0.787，p < 0.21（β = 4.752，p < 0.071），[相关因素2]（β = 1.154，p < 0.256）。