Research has demonstrated that hypoxia, a decrease in intracellular oxygen, is linked to multiple processes in the skin, including metabolic adaptation, cell survival, pathogenic microbe infection, immune response, tumorigenesis, and various diseases. This paper aims to perform a thorough bibliometric analysis of studies of hypoxia in skin health and disease to identify the frontiers, hotspots, and evolution of these studies. Articles about hypoxia in skin health and disease in the Web of Science Core Collection were gathered as of December 31, 2023. To find bursting keywords and references, VOSviewer was used to look at co-authorship and phrase co-occurrences and make visualizations of them. A total of 1511 papers on hypoxia in skin health and disease were examined in this study. China, the United States, and Japan were the top three countries contributing to this topic, while the was the journal with the most articles. In terms of prolific authors in the publications, Yuesheng Huang from China contributed the most articles. The terms "hypoxia," "angiogenesis," and "wound healing" were the ones that were used the most frequently. In this study, a bibliometric analysis was performed on the last 10 years' worth of research on hypoxia in skin health and disease. The analysis identified the publications, nations, authors, institutions, and journals that were involved in this subject. These data offer a more comprehensive understanding of the area of research that has been conducted on hypoxia in skin health and disease.